2AK4

Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide

Summary for 2AK4

• Entry DOI: 10.2210/pdb2ak4/pdb
• Related: 1ZHL
• Descriptor: HLA-B35 variant, Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, ... (7 entities in total)
• Functional Keywords: t cell receptor, bulged epitopes, pmhc-tcr complex, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P61769
• Total number of polymer chains: 20
• Total formula weight: 390028.74

Authors

Tynan, F.E.,Burrows, S.R.,Buckle, A.M.,Clements, C.S.,Borg, N.A.,Miles, J.J.,Beddoe, T.,Whisstock, J.C.,Wilce, M.C.,Silins, S.L.,Burrows, J.M.,Kjer-Nielsen, L.,Konstenko, L.,Purcell, A.W.,McCluskey, J.,Rossjohn, J. (deposition date: 2005-08-03, release date: 2005-10-11, Last modification date: 2011-07-13)

• Primary citation: Tynan, F.E.,Burrows, S.R.,Buckle, A.M.,Clements, C.S.,Borg, N.A.,Miles, J.J.,Beddoe, T.,Whisstock, J.C.,Wilce, M.C.,Silins, S.L.,Burrows, J.M.,Kjer-Nielsen, L.,Kostenko, L.,Purcell, A.W.,McCluskey, J.,Rossjohn, J.; T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide; Nat.Immunol., 6:1114-1122, 2005; PubMed: 16186824; DOI: 10.1038/ni1257

Experimental method

X-RAY DIFFRACTION (2.5 Å)