1JHT
Crystal structure of HLA-A2*0201 in complex with a nonameric altered peptide ligand (ALGIGILTV) from the MART-1/Melan-A.
Summary for 1JHT
Entry DOI | 10.2210/pdb1jht/pdb |
Related | 1JF1 |
Descriptor | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, nonameric peptide ligand from the MART-1/Melan-A, ... (4 entities in total) |
Functional Keywords | human, tumor immunity, melanoma antigen, mhc, vaccination, melanoma, class i, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 44589.62 |
Authors | Sliz, P.,Michielin, O.,Karplus, M.,Romero, P.,Wiley, D. (deposition date: 2001-06-28, release date: 2001-09-14, Last modification date: 2023-08-16) |
Primary citation | Sliz, P.,Michielin, O.,Cerottini, J.C.,Luescher, I.,Romero, P.,Karplus, M.,Wiley, D.C. Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes. J.Immunol., 167:3276-3284, 2001 Cited by PubMed: 11544315PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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