1RTJ
MECHANISM OF INHIBITION OF HIV-1 REVERSE TRANSCRIPTASE BY NON-NUCLEOSIDE INHIBITORS
Summary for 1RTJ
Entry DOI | 10.2210/pdb1rtj/pdb |
Descriptor | HIV-1 REVERSE TRANSCRIPTASE (3 entities in total) |
Functional Keywords | hiv-1 reverse transcriptase, nucleotidyltransferase |
Biological source | Human immunodeficiency virus 1 More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 P04585 |
Total number of polymer chains | 2 |
Total formula weight | 115994.00 |
Authors | Ren, J.,Esnouf, R.,Ross, C.,Jones, Y.,Stammers, D.,Stuart, D. (deposition date: 1995-05-03, release date: 1996-04-03, Last modification date: 2024-06-05) |
Primary citation | Esnouf, R.,Ren, J.,Ross, C.,Jones, Y.,Stammers, D.,Stuart, D. Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors. Nat.Struct.Biol., 2:303-308, 1995 Cited by PubMed: 7540935DOI: 10.1038/nsb0495-303 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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