1RTH

HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES

Summary for 1RTH
DescriptorHIV-1 REVERSE TRANSCRIPTASE, 6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE, ... (4 entities in total)
Functional Keywordshiv-1 reverse transcriptase, nucleotidyltransferase
Biological sourceHuman immunodeficiency virus 1
More
Cellular locationMatrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 P04585
Total number of polymer chains2
Total formula weight116292.29
Authors
Ren, J.,Esnouf, R.,Garman, E.,Somers, D.,Ross, C.,Kirby, I.,Keeling, J.,Darby, G.,Jones, Y.,Stuart, D.,Stammers, D. (deposition date: 1995-05-03, release date: 1996-04-03, Last modification date: 2011-07-13)
Primary citationDarby, G.,Esnouf, R.,Garman, E.,Jones, Y.,Keeling, J.,Kirby, I.,Ren, J.,Ross, C.,Somers, D.,Stuart, D.
High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
Nat.Struct.Biol., 2:293-302, 1995
PubMed: 7540934
DOI: 110.1038/nsb0495-293
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation
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PDB entries from 2021-06-09