Author results

1HNF
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE HUMAN CELL ADHESION MOLECULE CD2 AT 2.5 ANGSTROMS RESOLUTION
Descriptor:CD2, N-ACETYL-D-GLUCOSAMINE, SODIUM ION
Authors:Bodian, D.L., Jones, E.Y., Harlos, K., Stuart, D.I., Davis, S.J.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
Structure, 2, 1994
1HNG
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CRYSTAL STRUCTURE AT 2.8 ANGSTROMS RESOLUTION OF A SOLUBLE FORM OF THE CELL ADHESION MOLECULE CD2
Descriptor:CD2
Authors:Jones, E.Y., Davis, S.J., Williams, A.F., Harlos, K., Stuart, D.I.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2.
Nature, 360, 1992
1CCZ
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CRYSTAL STRUCTURE OF THE CD2-BINDING DOMAIN OF CD58 (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3) AT 1.8-A RESOLUTION
Descriptor:PROTEIN (CD58), N-ACETYL-D-GLUCOSAMINE
Authors:Ikemizu, S., Sparks, L.M., Van Der Merwe, P.A., Harlos, K., Stuart, D.I., Jones, E.Y., Davis, S.J.
Deposit date:1999-03-02
Release date:1999-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution.
Proc.Natl.Acad.Sci.USA, 96, 1999
1DR9
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CRYSTAL STRUCTURE OF A SOLUBLE FORM OF B7-1 (CD80)
Descriptor:T LYMPHOCYTE ACTIVATION ANTIGEN, N-ACETYL-D-GLUCOSAMINE
Authors:Ikemizu, S., Jones, E.Y., Stuart, D.I., Davis, S.J.
Deposit date:2000-01-06
Release date:2000-01-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and dimerization of a soluble form of B7-1.
Immunity, 12, 2000
1ERG
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS
Descriptor:CD59
Authors:Kieffer, B., Driscoll, P.C., Campbell, I.D., Willis, A.C., Van Der Merwe, P.A., Davis, S.J.
Deposit date:1993-12-13
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins.
Biochemistry, 33, 1994
1ERH
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS
Descriptor:CD59
Authors:Kieffer, B., Driscoll, P.C., Campbell, I.D., Willis, A.C., Van Der Merwe, P.A., Davis, S.J.
Deposit date:1993-12-13
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins.
Biochemistry, 33, 1994
1OLZ
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THE LIGAND-BINDING FACE OF THE SEMAPHORINS REVEALED BY THE HIGH RESOLUTION CRYSTAL STRUCTURE OF SEMA4D
Descriptor:SEMAPHORIN 4D
Authors:Love, C.A., Harlos, K., Mavaddat, N., Davis, S.J., Stuart, D.I., Jones, E.Y., Esnouf, R.M.
Deposit date:2003-08-19
Release date:2003-09-11
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Ligand-Binding Face of the Semaphorins Revealed by the High-Resolution Crystal Structure of Sema4D
Nat.Struct.Biol., 10, 2003
1YJD
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CRYSTAL STRUCTURE OF HUMAN CD28 IN COMPLEX WITH THE FAB FRAGMENT OF A MITOGENIC ANTIBODY (5.11A1)
Descriptor:Fab fragment of 5.11A1 antibody light chain, Fab fragment of 5.11A1 antibody heavy chain, T-cell-specific surface glycoprotein CD28, ...
Authors:Evans, E.J., Esnouf, R.M., Manso-Sancho, R., Gilbert, R.J.C., James, J.R., Sorensen, P., Stuart, D.I., Davis, S.J.
Deposit date:2005-01-14
Release date:2005-02-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a soluble CD28-Fab complex
Nat.Immunol., 6, 2005
2DRU
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CRYSTAL STRUCTURE AND BINDING PROPERTIES OF THE CD2 AND CD244 (2B4) BINDING PROTEIN, CD48
Descriptor:chimera of CD48 antigen and T-cell surface antigen CD2, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Evans, E.J., Ikemizu, S., Davis, S.J.
Deposit date:2006-06-15
Release date:2006-07-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure and Binding Properties of the CD2 and CD244 (2B4)-binding Protein, CD48
J.Biol.Chem., 281, 2006
2M2D
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HUMAN PROGRAMMED CELL DEATH 1 RECEPTOR
Descriptor:Programmed cell death protein 1
Authors:Veverka, V., Cheng, X., Waters, L.C., Muskett, F.W., Morgan, S., Lesley, A., Griffiths, M., Stubberfield, C., Griffin, R., Henry, A.J., Robinson, M.K., Jansson, A., Ladbury, J.E., Ikemizu, S., Davis, S.J., Carr, M.D.
Deposit date:2012-12-18
Release date:2013-02-27
Last modified:2013-05-15
Method:SOLUTION NMR
Cite:Structure and interactions of the human programmed cell death 1 receptor.
J.Biol.Chem., 288, 2013
2V5Y
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CRYSTAL STRUCTURE OF THE RECEPTOR PROTEIN TYROSINE PHOSPHATASE MU ECTODOMAIN
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, N-ACETYL-D-GLUCOSAMINE, SODIUM ION
Authors:Aricescu, A.R., Siebold, C., Choudhuri, K., Chang, V.T., Lu, W., Davis, S.J., van der Merwe, P.A., Jones, E.Y.
Deposit date:2007-07-11
Release date:2007-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism.
Science, 317, 2007
2X44
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STRUCTURE OF A STRAND-SWAPPED DIMERIC FORM OF CTLA-4
Descriptor:CYTOTOXIC T-LYMPHOCYTE PROTEIN 4
Authors:Sonnen, A.F.-P., Yu, C., Evans, E.J., Stuart, D.I., Davis, S.J., Gilbert, R.J.C.
Deposit date:2010-01-28
Release date:2010-04-07
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Domain Metastability: A Molecular Basis for Immunoglobulin Deposition?
J.Mol.Biol., 399, 2010
2Z3Q
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CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX
Descriptor:Interleukin-15, Interleukin-15 receptor alpha chain
Authors:Chirifu, M., Yamagata, Y., Davis, S.J., Ikemizu, S.
Deposit date:2007-06-05
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
2Z3R
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CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX
Descriptor:Interleukin-15, Interleukin-15 receptor alpha chain, GLYCEROL
Authors:Chirifu, M., Yamagata, Y., Davis, S.J., Ikemizu, S.
Deposit date:2007-06-05
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
3OSK
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CRYSTAL STRUCTURE OF HUMAN CTLA-4 APO HOMODIMER
Descriptor:Cytotoxic T-lymphocyte protein 4, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Yu, C., Sonnen, A.F.-P., Ikemizu, S., Stuart, D.I., Gilbert, R.J.C., Davis, S.J.
Deposit date:2010-09-09
Release date:2010-12-08
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering
J.Biol.Chem., 286, 2011
5FMV
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CRYSTAL STRUCTURE OF HUMAN CD45 EXTRACELLULAR REGION, DOMAINS D1-D4
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-09
Release date:2016-03-23
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN6
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CRYSTAL STRUCTURE OF HUMAN CD45 EXTRACELLULAR REGION, DOMAINS D1-D3
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-10
Release date:2016-03-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN7
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CRYSTAL STRUCTURE OF HUMAN CD45 EXTRACELLULAR REGION, DOMAINS D1-D2
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE, MERCURY (II) ION
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-10
Release date:2016-03-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN8
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CRYSTAL STRUCTURE OF RAT CD45 EXTRACELLULAR REGION, DOMAINS D3-D4
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE, CITRATE ANION
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-11
Release date:2016-03-23
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
1CID
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CRYSTAL STRUCTURE OF DOMAINS 3 & 4 OF RAT CD4 AND THEIR RELATIONSHIP TO THE NH2-TERMINAL DOMAINS
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4, SULFATE ION
Authors:Brady, R.L., Dodson, E.J., Lange, G.
Deposit date:1993-01-28
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains.
Science, 260, 1993
1I8L
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HUMAN B7-1/CTLA-4 CO-STIMULATORY COMPLEX
Descriptor:T LYMPHOCYTE ACTIVATION ANTIGEN CD80, CYTOTOXIC T-LYMPHOCYTE PROTEIN 4, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Stamper, C.C., Somers, W.S., Mosyak, L.
Deposit date:2001-03-14
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses.
Nature, 410, 2001
3R06
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CRYSTAL STRUCTURE OF ANTI-MOUSE CD3EPSILON ANTIBODY 2C11 FAB FRAGMENT
Descriptor:anti-mouse CD3epsilon antibody 2C11 Fab light chain, anti-mouse CD3epsilon antibody 2C11 Fab heavy chain
Authors:Shore, D.A., Zhu, X., Wilson, I.A.
Deposit date:2011-03-07
Release date:2012-01-25
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
J.Biol.Chem., 287, 2012
3R08
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CRYSTAL STRUCTURE OF MOUSE CD3EPSILON IN COMPLEX WITH ANTIBODY 2C11 FAB
Descriptor:Mouse anti-mouse CD3epsilon antibody 2C11 light chain, Mouse anti-mouse CD3epsilon antibody 2C11 heavy chain, T-cell surface glycoprotein CD3 epsilon chain
Authors:Shore, D.A., Zhu, X., Wilson, I.A.
Deposit date:2011-03-07
Release date:2012-01-25
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
J.Biol.Chem., 287, 2012