Author results

3HG1
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GERMLINE-GOVERNED RECOGNITION OF A CANCER EPITOPE BY AN IMMUNODOMINANT HUMAN T CELL RECEPTOR
Descriptor:MHC class I antigen, Beta-2-microglobulin, CANCER/MART-1, ...
Authors:Cole, D.K., Yuan, F., Rizkallah, P.J., Miles, J.J., Gostick, E., Price, D.A., Gao, G.F., Jakobsen, B.K., Sewell, A.K.
Deposit date:2009-05-13
Release date:2009-07-28
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
J.Biol.Chem., 284, 2009
2BCK
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CRYSTAL STRUCTURE OF HLA-A*2402 COMPLEXED WITH A TELOMERASE PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-24 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Jakobsen, B.K., Cole, D.K., Gao, G.F.
Deposit date:2005-10-19
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
2HP4
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COMPUTATIONAL DESIGN AND CRYSTAL STRUCTURE OF AN ENHANCED AFFINITY MUTANT HUMAN CD8-ALPHA-ALPHA CO-RECEPTOR
Descriptor:T-cell surface glycoprotein CD8 alpha chain, SULFATE ION, GLYCEROL
Authors:Rizkallah, P.J., Cole, D.K., Jakobsen, B.K., Boulter, J.M., Glick, M., Gao, G.F.
Deposit date:2006-07-17
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
4MNQ
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TCR-PEPTIDE SPECIFICITY OVERRIDES AFFINITY ENHANCING TCR-MHC INTERACTIONS
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Jakobsen, B.K.
Deposit date:2013-09-11
Release date:2013-11-13
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.742 Å)
Cite:T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
J.Biol.Chem., 289, 2014
5C07
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING YQFGPDFPIA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C08
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1E6 TCR IN COMPLEX WITH HLA-A0E CARRYING RQWGPDPAAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C09
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HLA CLASS I HISTOCOMPATIBILITY ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.475 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0A
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING MVW PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0B
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING RQFGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0C
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING RQFGPDWIVA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.974 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0D
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HLA-A02 CARRYING AQWGPDPAAA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0E
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HLA-A02 CARRYING YLGGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0F
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HLA-A02 CARRYING RQWGPDPAAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0G
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HLA-A02 CARRYING YLGGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0I
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HAL-A02 CARRYING RQFGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0J
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HLA-A02 CARRYING RQFGPDWIVA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5MEN
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILAKFLHWL, IN COMPLEX WITH COGNATE T-CELL RECEPTOR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Lloyd, A., Crowther, M., Cole, D.K., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEO
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HUMAN LEUKOCYTE ANTIGEN PRESENTING ILGKFLHRL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Lloyd, A., Crowther, M., Cole, D.K., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.772 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEP
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILGKFLHWL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Lloyd, A., Crowther, M., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEQ
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILAKFLHTL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Lloyd, A., Crowther, M., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MER
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILAKFLHEL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Lloyd, A., Crowther, M., Cole, D.K., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5N1Y
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HLA-A02 CARRYING MVWGPDPLYV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2017-02-06
Release date:2017-02-15
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J. Clin. Invest., 126, 2016
5NMD
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868 TCR SPECIFIC FOR HLA A02 PRESENTING HIV EPITOPE SLYNTVATL
Descriptor:human T-cell Receptor alpha chain, Human T-cell Receptor, beta chain, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NME
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868 TCR IN COMPLEX WITH HLA A02 PRESENTING SLYNTVATL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMF
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868 TCR IN COMPLEX WITH HLA A02 PRESENTING SLYNTIATL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017