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6DNW
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SEQUENCE REQUIREMENTS OF THE LISTERIA INNOCUA PROPHAGE ATTP SITE
Descriptor:Putative integrase [Bacteriophage A118], DNA (26-MER), ZINC ION
Authors:Li, H., Sharp, R., Rutherford, K., Gupta, K., Van Duyne, G.D.
Deposit date:2018-06-08
Release date:2018-10-03
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Serine Integrase attP Binding and Specificity.
J. Mol. Biol., 430, 2018
6EDQ
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CRYSTAL STRUCTURE OF THE LIGHT-GATED ANION CHANNELRHODOPSIN GTACR1
Descriptor:Anion channelrhodopsin 1, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Li, H., Huang, C.Y., Wang, M., Zheng, L., Spudich, J.L.
Deposit date:2018-08-10
Release date:2019-01-16
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a natural light-gated anion channelrhodopsin.
Elife, 8, 2019
4TMP
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CRYSTAL STRUCTURE OF AF9 YEATS BOUND TO H3K9AC PEPTIDE
Descriptor:Protein AF-9, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, 1,2-ETHANEDIOL
Authors:Li, H., Li, Y., Wang, H., Ren, Y.
Deposit date:2014-06-02
Release date:2014-11-05
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
5B73
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CRYSTAL STRUCTURE OF HUMAN ZMYND8 PHD-BROMO-PWWP DOMAIN
Descriptor:Protein kinase C-binding protein 1, ZINC ION
Authors:Li, H., Li, Y., Zheng, X.
Deposit date:2016-06-03
Release date:2016-11-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes
Mol.Cell, 63, 2016
3OWG
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CRYSTAL STRUCTURE OF VACCINIA VIRUS POLYADENYLATE POLYMERASE(VP55)
Descriptor:Poly(A) polymerase catalytic subunit
Authors:Li, C., Li, H., Zhou, S., Gershon, P.D., Poulos, T.L.
Deposit date:2010-09-17
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid.
Acta Crystallogr.,Sect.D, 69, 2013
5ZAZ
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SOLUTION STRUCTURE OF INTEGRIN B2 MONOMER TRANMEMBRANE DOMAIN IN BICELLE
Descriptor:Integrin beta-2
Authors:Li, H., Guo, J., Xu, C.
Deposit date:2018-02-09
Release date:2018-10-17
Last modified:2018-11-28
Method:SOLUTION NMR
Cite:Intramembrane ionic protein-lipid interaction regulates integrin structure and function.
PLoS Biol., 16, 2018
2NAE
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MEMBRANE-BOUND MOUSE CD28 CYTOPLASMIC TAIL
Descriptor:T-cell-specific surface glycoprotein CD28
Authors:Li, H., Xu, C., Pan, W.
Deposit date:2015-12-23
Release date:2016-12-21
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Dynamic regulation of CD28 conformation and signaling by charged lipids and ions
Nat. Struct. Mol. Biol., 2017
3FP9
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CRYSTAL STRUCTURE OF INTERN DOMAIN OF PROTEASOME-ASSOCIATED ATPASE, MYCOBACTERIUM TUBERCULOSIS
Descriptor:Proteasome-associated ATPase
Authors:Li, H., Wang, T.
Deposit date:2009-01-04
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights on the Mycobacterium tuberculosis Proteasomal ATPase Mpa.
Structure, 17, 2009
5IQL
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CRYSTAL STRUCTURE OF YEATS2 YEATS BOUND TO H3K27CR PEPTIDE
Descriptor:YEATS domain-containing protein 2, Histone H3.1
Authors:Li, H., Zhao, D., Guan, H.
Deposit date:2016-03-11
Release date:2016-07-20
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:YEATS2 is a selective histone crotonylation reader.
Cell Res., 26, 2016
4QBQ
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CRYSTAL STRUCTURE OF DNMT3A ADD DOMAIN BOUND TO H3 PEPTIDE
Descriptor:DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
Authors:Li, H., Patel, D.J.
Deposit date:2014-05-08
Release date:2015-05-13
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
1FV1
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STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, MYELIN BASIC PROTEIN, ...
Authors:Li, H., Mariuzza, A.R., Li, Y., Martin, R.
Deposit date:2000-09-18
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins.
J.Mol.Biol., 304, 2000
5EIB
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CRYSTAL STRUCTURE OF CPAP PN2-3 C-TERMINAL LOOP-HELIX IN COMPLEX WITH DARPIN-TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed ankyrin repeat protein, ...
Authors:Li, H., Zheng, X.
Deposit date:2015-10-29
Release date:2016-10-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length
Nat Commun, 7, 2016
1BU7
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CRYOGENIC STRUCTURE OF CYTOCHROME P450BM-3 HEME DOMAIN
Descriptor:PROTEIN (CYTOCHROME P450), PROTOPORPHYRIN IX CONTAINING FE, 1,2-ETHANEDIOL
Authors:Li, H., Poulos, T.L.
Deposit date:1998-09-14
Release date:1998-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of a cytochrome P450-redox partner electron-transfer complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
1DQJ
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CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor:ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), LYSOZYME
Authors:Li, H., Mariuzza, R.A.
Deposit date:2000-01-04
Release date:2000-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
1DQM
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CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY
Descriptor:ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN)
Authors:Li, H., Mariuzza, R.A.
Deposit date:2000-01-04
Release date:2000-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
1DQQ
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CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY HYHEL-63
Descriptor:ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN)
Authors:Li, H., Mariuzza, R.A.
Deposit date:2000-01-04
Release date:2000-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
1ED4
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH IPITU (H4B FREE)
Descriptor:NITRIC OXIDE SYNTHASE, ACETATE ION, ZINC ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Kral, V., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-01-26
Release date:2000-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
J.Inorg.Biochem., 81, 2000
1ED6
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-NIO (H4B FREE)
Descriptor:NITRIC OXIDE SYNTHASE, ACETATE ION, ZINC ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-01-26
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Biochemistry, 40, 2001
1FOI
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1400W(H4B-FREE)
Descriptor:NITRIC-OXIDE SYNTHASE, ACETATE ION, CACODYLATE ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Biochemistry, 40, 2001
1FOL
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REDUCED BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG(H4B-FREE)
Descriptor:NITRIC-OXIDE SYNTHASE, CACODYLATE ION, ACETATE ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors
Biochemistry, 40, 2001
1FOO
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-FREE)
Descriptor:NITRIC-OXIDE SYNTHASE, CACODYLATE ION, ACETATE ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Biochemistry, 40, 2001
1FOP
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-BOUND)
Descriptor:NITRIC-OXIDE SYNTHASE, CACODYLATE ION, ACETATE ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Biochemistry, 40, 2001
3UFO
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STRUCTURE OF RAT NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH 6-(((3S,4S)-4-((5-(3-FLUOROPHENYL)PENTYL)OXY)PYRROLIDIN-3-YL)METHYL)-4-METHYLPYRIDIN-2-AMINE
Descriptor:Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2011-11-01
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.169 Å)
Cite:Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations.
J.Am.Chem.Soc., 134, 2012
3UFP
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STRUCTURE OF RAT NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH 6-(((3R,4R)-4-((5-(3-FLUOROPHENYL)PENTYL)OXY)PYRROLIDIN-3-YL)METHYL)-4-METHYLPYRIDIN-2-AMINE
Descriptor:Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2011-11-01
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations.
J.Am.Chem.Soc., 134, 2012
3UFQ
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STRUCTURE OF RAT NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH 6-(((3S,4S)-4-(((E)-5-(3-FLUOROPHENYL)PENT-4-EN-1-YL)OXY)PYRROLIDIN-3-YL)METHYL)-4-METHYLPYRIDIN-2-AMINE
Descriptor:Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2011-11-01
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.058 Å)
Cite:Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations.
J.Am.Chem.Soc., 134, 2012