4D1P

Structure of human endothelial nitric oxide synthase heme domain IN COMPLEX WITH 6-((((3S, 5R)-5-(((6-AMINO-4-METHYLPYRIDIN-2-YL)METHOXY) METHYL)PYRROLIDIN-3-YL)OXY) METHYL)-4-METHYLPYRIDIN-2-AMINE

Summary for 4D1P

Entry DOI	10.2210/pdb4d1p/pdb
Related	4D1N 4D1O
Descriptor	NITRIC OXIDE SYNTHASE, ENDOTHELIAL, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (10 entities in total)
Functional Keywords	oxidoreductase, nitric oxide synthase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cell membrane: P29474
Total number of polymer chains	2
Total formula weight	102667.05
Authors	Li, H.,Poulos, T.L. (deposition date: 2014-05-02, release date: 2014-10-15, Last modification date: 2023-12-20)
Primary citation	Li, H.,Jamal, J.,Plaza, C.,Pineda, S.H.,Chreifi, G.,Jing, Q.,Cinelli, M.A.,Silverman, R.B.,Poulos, T.L. Structures of Human Constitutive Nitric Oxide Synthases Acta Crystallogr.,Sect.D, 70:2667-, 2014 Cited by PubMed: 25286850 DOI: 10.1107/S1399004714017064 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.731 Å)

Structure validation