4CX2
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL) PYRROLIDIN-3-YL)OXY)PENTYL)-4-METHYLPYRIDIN-2-AMINE
Summary for 4CX2
Entry DOI | 10.2210/pdb4cx2/pdb |
Related | 4CWV 4CWW 4CWX 4CWY 4CWZ 4CX0 4CX1 4CX3 4CX4 4CX5 4CX6 4CX7 |
Descriptor | NITRIC OXIDE SYNTHASE, ENDOTHELIAL, PROTOPORPHYRIN IX CONTAINING FE, 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, ... (7 entities in total) |
Functional Keywords | oxidoreductase, inhibitor complex |
Biological source | BOS TAURUS (CATTLE) |
Cellular location | Cell membrane: P29473 |
Total number of polymer chains | 2 |
Total formula weight | 102149.95 |
Authors | Li, H.,Poulos, T.L. (deposition date: 2014-04-03, release date: 2014-08-13, Last modification date: 2014-09-03) |
Primary citation | Li, H.,Jamal, J.,Delker, S.L.,Plaza, C.,Ji, H.,Jing, Q.,Huang, H.,Kang, S.,Silverman, R.B.,Poulos, T.L. Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases. Biochemistry, 53:5272-, 2014 Cited by PubMed: 25089924DOI: 10.1021/BI500561H PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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