Author results

2TOB
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SOLUTION STRUCTURE OF THE TOBRAMYCIN-RNA APTAMER COMPLEX, NMR, 13 STRUCTURES
Descriptor:RNA (5'-R(*AP*CP*UP*UP*GP*GP*UP*UP*UP*AP*GP*GP*UP*AP*AP*UP*GP*AP*GP*U)-3'), 3-DEOXY-3-AMINO GLUCOSE, 2,3,6-TRIDEOXY-2,6-DIAMINO GLUCOSE, ...
Authors:Jiang, L., Patel, D.J.
Deposit date:1998-06-17
Release date:1999-06-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the tobramycin-RNA aptamer complex.
Nat.Struct.Biol., 5, 1998
3CZ3
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CRYSTAL STRUCTURE OF TOMATO ASPERMY VIRUS 2B IN COMPLEX WITH SIRNA
Descriptor:RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*A)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*G)-3'), Protein 2b
Authors:Ma, J.B., Li, F., Ding, S.W., Patel, D.J.
Deposit date:2008-04-27
Release date:2009-05-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structural Basis for siRNA Recognition by 2b, a Viral Suppressor of Non-Cell Autonomous RNA Silencing
To be Published
3D1B
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TETRAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
Descriptor:RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H., Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D1D
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HEXAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
Descriptor:RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H., Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D2N
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CRYSTAL STRUCTURE OF MBNL1 TANDEM ZINC FINGER 1 AND 2 DOMAIN
Descriptor:Muscleblind-like protein 1, ZINC ION
Authors:Teplova, M., Patel, D.J.
Deposit date:2008-05-08
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nat.Struct.Mol.Biol., 15, 2008
3D2Q
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CRYSTAL STRUCTURE OF MBNL1 TANDEM ZINC FINGER 3 AND 4 DOMAIN
Descriptor:Muscleblind-like protein 1, ZINC ION
Authors:Teplova, M., Patel, D.J.
Deposit date:2008-05-08
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nat.Struct.Mol.Biol., 15, 2008
3D2S
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CRYSTAL STRUCTURE OF MBNL1 TANDEM ZINC FINGER 3 AND 4 DOMAIN IN COMPLEX WITH CGCUGU RNA
Descriptor:5'-R(*CP*GP*CP*UP*GP*U)-3', Muscleblind-like protein 1, ZINC ION
Authors:Teplova, M., Patel, D.J.
Deposit date:2008-05-08
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nat.Struct.Mol.Biol., 15, 2008
3DLB
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CRYSTAL STRUCTURE OF THE GUIDE-STRAND-CONTAINING ARGONAUTE PROTEIN SILENCING COMPLEX
Descriptor:argonaute, DNA (5'-D(*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DA)-3')
Authors:Wang, Y., Sheng, G., Patel, D.J.
Deposit date:2008-06-26
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the guide-strand-containing argonaute silencing complex.
Nature, 456, 2008
3DLH
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CRYSTAL STRUCTURE OF THE GUIDE-STRAND-CONTAINING ARGONAUTE PROTEIN SILENCING COMPLEX
Descriptor:Argonaute, DNA (5'-D(DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DAP*DTP*DAP*DGP*DT)-3'), MAGNESIUM ION, ...
Authors:Wang, Y., Sheng, G., Patel, D.J.
Deposit date:2008-06-27
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the guide-strand-containing argonaute silencing complex.
Nature, 456, 2008
3F73
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ALIGNMENT OF GUIDE-TARGET SEED DUPLEX WITHIN AN ARGONAUTE SILENCING COMPLEX
Descriptor:ARGONAUTE, DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*AP*A*CP*UP*CP*AP*CP*UP*AP*CP*CP*UP*CP*GP*U)-3'), ...
Authors:Wang, Y., Li, H., Sheng, G., Juranek, S., Tuschl, T., Patel, D.J.
Deposit date:2008-11-07
Release date:2008-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.
Nature, 456, 2008
3GII
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DPO4 EXTENSION TERNARY COMPLEX WITH DISORDERED A OPPOSITE AN OXOG IN ANTI CONFORMATION
Descriptor:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ...
Authors:Rechkoblit, O., Malinina, L., Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIJ
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DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(SYN)-A(ANTI) AND OXOG(ANTI)-A(SYN) PAIRS
Descriptor:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
Authors:Rechkoblit, O., Malinina, L., Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIK
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DPO4 EXTENSION TERNARY COMPLEX WITH THE OXOG(ANTI)-C(ANTI) PAIR
Descriptor:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DOC))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
Authors:Rechkoblit, O., Malinina, L., Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIL
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DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(ANTI)-T(ANTI) PAIR
Descriptor:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DT))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
Authors:Rechkoblit, O., Malinina, L., Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIM
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DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(ANTI)-G(SYN) PAIR
Descriptor:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DDG))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
Authors:Rechkoblit, O., Malinina, L., Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GL6
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CRYSTAL STRUCTURE OF JARID1A-PHD3 COMPLEXED WITH H3(1-9)K4ME3 PEPTIDE
Descriptor:Histone demethylase JARID1A, Histone H3, ZINC ION
Authors:Wang, Z., Song, J., Patel, D.J.
Deposit date:2009-03-11
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
3HJF
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE E546 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 15-NT RNA TARGET STRAND
Descriptor:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
Authors:Wang, Y., Li, H., Sheng, G., Patel, D.J.
Deposit date:2009-05-21
Release date:2009-10-06
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.056 Å)
Cite:Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HK2
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE N478 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 19-NT RNA TARGET STRAND
Descriptor:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
Authors:Wang, Y., Li, H., Sheng, G., Patel, D.J.
Deposit date:2009-05-22
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HM9
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE COMPLEXED WITH DNA GUIDE STRAND AND 19-NT RNA TARGET STRAND
Descriptor:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
Authors:Wang, Y., Li, H., Sheng, G., Patel, D.J.
Deposit date:2009-05-28
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HO1
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE N546 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 12-NT RNA TARGET STRAND
Descriptor:argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*T*AP*GP*T)-3', 5'-R(P*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
Authors:Wang, Y., Li, H., Sheng, G., Patel, D.J.
Deposit date:2009-06-01
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HVR
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE COMPLEXED WITH DNA GUIDE STRAND AND 19-NT RNA TARGET STRAND WITH TWO MG2+ AT THE CLEAVAGE SITE
Descriptor:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*TP*GP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
Authors:Wang, Y., Li, H., Sheng, G., Patel, D.J.
Deposit date:2009-06-16
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.211 Å)
Cite:Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HXM
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STRUCTURE OF AN ARGONAUTE COMPLEXED WITH GUIDE DNA AND TARGET RNA DUPLEX CONTAINING TWO MISMATCHES.
Descriptor:Argonaute, DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*UP*CP*AP*CP*UP*AP*CP*CP*UP*CP*GP*U)-3'), ...
Authors:Wang, Y., Li, H., Sheng, G., Patel, D.J.
Deposit date:2009-06-21
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3K94
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CRYSTAL STRUCTURE OF THIAMIN PYROPHOSPHOKINASE FROM GEOBACILLUS THERMODENITRIFICANS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET GTR2
Descriptor:Thiamin pyrophosphokinase
Authors:Kuzin, A., Su, M., Seetharaman, J., Janjua, J., Xiao, R., Patel, D.J., Ciccosanti, C., Lee, D., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-10-15
Release date:2010-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Northeast Structural Genomics Consortium Target GtR2
To be Published
3KHG
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DPO4 EXTENSION TERNARY COMPLEX WITH MISINSERTED A OPPOSITE THE 2-AMINOFLUORENE-GUANINE [AF]G LESION
Descriptor:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*C*CP*TP*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ...
Authors:Rechkoblit, O., Malinina, L., Patel, D.J.
Deposit date:2009-10-30
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
Nat.Struct.Mol.Biol., 17, 2010
3KHH
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DPO4 EXTENSION TERNARY COMPLEX WITH A C BASE OPPOSITE THE 2-AMINOFLUORENE-GUANINE [AF]G LESION
Descriptor:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DOC))-3', 5'-D(*CP*CP*TP*A*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ...
Authors:Rechkoblit, O., Malinina, L., Patel, D.J.
Deposit date:2009-10-30
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
Nat.Struct.Mol.Biol., 17, 2010