6CGE
| Crystal structure of human 17beta-HSD type 1 in ternary complex with PBRM and NADP+ | Descriptor: | 3-{[(14beta,16alpha,17alpha)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide, Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, T, Lin, S.X. | Deposit date: | 2018-02-20 | Release date: | 2019-01-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Combined Biophysical Chemistry Reveals a New Covalent Inhibitor with a Low-Reactivity Alkyl Halide. J Phys Chem Lett, 9, 2018
|
|
8IAG
| |
8Z6G
| |
1AKH
| MAT A1/ALPHA2/DNA TERNARY COMPLEX | Descriptor: | DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ... | Authors: | Li, T, Jin, Y, Vershon, A.K, Wolberger, C. | Deposit date: | 1997-05-19 | Release date: | 1998-05-20 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract. Nucleic Acids Res., 26, 1998
|
|
6DTP
| |
1KU5
| Crystal Structure of recombinant histone HPhA from hyperthermophilic archaeon Pyrococcus horikoshii OT3 | Descriptor: | ACETATE ION, HPhA, SULFATE ION | Authors: | Li, T, Sun, F, Ji, X, Feng, Y, Rao, Z. | Deposit date: | 2002-01-21 | Release date: | 2003-08-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure based hyperthermostability of archaeal histone HPhA from Pyrococcus horikoshii J.MOL.BIOL., 325, 2003
|
|
1YRN
| CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA | Descriptor: | DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*TP*AP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*TP*AP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT A1 HOMEODOMAIN), ... | Authors: | Li, T, Stark, M.R, Johnson, A.D, Wolberger, C. | Deposit date: | 1995-11-02 | Release date: | 1996-01-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA. Science, 270, 1995
|
|
7VPG
| Crystal structure of the C-terminal tail of SARS-CoV-1 Orf6 complex with human nucleoporin pair Rae1-Nup98 | Descriptor: | Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor | Authors: | Li, T, Guo, H, Yang, T, Wen, Y, Ji, X. | Deposit date: | 2021-10-17 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export. Front Mol Biosci, 8, 2021
|
|
7VPH
| Crystal structure of the C-terminal tail of SARS-CoV-2 Orf6 complex with human nucleoporin pair Rae1-Nup98 | Descriptor: | Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor | Authors: | Li, T, Guo, H, Yang, T, Wen, Y, Ji, X. | Deposit date: | 2021-10-17 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export. Front Mol Biosci, 8, 2021
|
|
7F5G
| The crystal structure of RBD-Nanobody complex, DL4 (SA4) | Descriptor: | ACETATE ION, GLYCEROL, Nanobody DL4, ... | Authors: | Li, T, Lai, Y, Zhou, Y, Tan, J, Li, D. | Deposit date: | 2021-06-22 | Release date: | 2022-05-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Isolation, characterization, and structure-based engineering of a neutralizing nanobody against SARS-CoV-2. Int.J.Biol.Macromol., 209, 2022
|
|
1MYM
| |
7C8V
| Structure of sybody SR4 in complex with the SARS-CoV-2 S Receptor Binding domain (RBD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... | Authors: | Li, T, Yao, H, Cai, H, Qin, W, Li, D. | Deposit date: | 2020-06-03 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
|
|
7C8W
| Structure of sybody MR17 in complex with the SARS-CoV-2 S receptor-binding domain (RBD) | Descriptor: | GLYCEROL, Spike protein S1, Synthetic nanobody MR17, ... | Authors: | Li, T, Cai, H, Yao, H, Qin, W, Li, D. | Deposit date: | 2020-06-03 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
|
|
7CAN
| Structure of sybody MR17-K99Y in complex with the SARS-CoV-2 S Receptor-binding domain (RBD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... | Authors: | Li, T, Yao, H, Cai, H, Qin, W, Li, D. | Deposit date: | 2020-06-09 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
|
|
5Z0R
| Structural insight into the Zika virus capsid encapsulating the viral genome | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | Deposit date: | 2017-12-20 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
|
|
5Z0V
| Structural insight into the Zika virus capsid encapsulating the viral genome | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | Deposit date: | 2017-12-21 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.913 Å) | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
|
|
3I7P
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A | Descriptor: | DNA damage-binding protein 1, WD repeat-containing protein 40A | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-08 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I7O
| Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1 | Descriptor: | DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1 | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-08 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I7N
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDTC1 | Descriptor: | DNA damage-binding protein 1, WD and tetratricopeptide repeats protein 1 | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-08 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I7H
| Crystal Structure of DDB1 in Complex with the H-Box Motif of HBX | Descriptor: | DNA damage-binding protein 1, X protein | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-08 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I7L
| Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2 | Descriptor: | DNA damage-binding protein 1, DNA damage-binding protein 2 | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-08 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I7K
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WHX | Descriptor: | DNA damage-binding protein 1, X protein | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-08 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I8E
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR42A | Descriptor: | DNA damage-binding protein 1, WD repeat-containing protein 42A | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-09 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I89
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR22 | Descriptor: | DNA damage-binding protein 1, WD repeat-containing protein 22 | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-09 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|
3I8C
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A | Descriptor: | DNA damage-binding protein 1, WD repeat-containing protein 21A | Authors: | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | Deposit date: | 2009-07-09 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
|
|