Author results

3ANN
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH QUINOLIN-2-YLMETHYLPHOSPHONIC ACID
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (quinolin-2-ylmethyl)phosphonic acid
著者Endo, K., Kato, M., Deng, L., Song, Y., Yajima, S.
登録日2010-09-03
公開日2011-02-23
最終更新日2011-10-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2, 2011
3J9B
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ELECTRON CRYO-MICROSCOPY OF AN RNA POLYMERASE
分子名称:Polymerase, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
著者Chang, S.H., Sun, D.P., Liang, H.H., Wang, J., Li, J., Guo, L., Wang, X.L., Guan, C.C., Boruah, B.M., Yuan, L.M., Feng, F., Yang, M.R., Wojdyla, J., Wang, J.W., Wang, M.T., Wang, H.W., Liu, Y.F.
登録日2014-12-16
公開日2015-02-18
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
3M06
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CRYSTAL STRUCTURE OF TRAF2
分子名称:TNF receptor-associated factor 2
著者Kabaleeswaran, V., Wu, H.
登録日2010-03-02
公開日2010-04-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
3M0A
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CRYSTAL STRUCTURE OF TRAF2:CIAP2 COMPLEX
分子名称:TNF receptor-associated factor 2, Baculoviral IAP repeat-containing protein 3, ZINC ION
著者Kabaleeswaran, V., Wu, H.
登録日2010-03-02
公開日2010-04-28
最終更新日2015-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
3M0D
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CRYSTAL STRUCTURE OF THE TRAF1:TRAF2:CIAP2 COMPLEX
分子名称:TNF receptor-associated factor 2, TNF receptor-associated factor 1, Baculoviral IAP repeat-containing protein 3, ...
著者Kabaleeswaran, V., Wu, H.
登録日2010-03-02
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
3RAS
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH A LIPOPHILIC PHOSPHONATE INHIBITOR
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(N-HYDROXYACETAMIDO)-1-(3,4-DICHLOROPHENYL)PROPYLPHOSPHONIC ACID, ...
著者Diao, J., Deng, L., Prasad, B.V.V., Song, Y.
登録日2011-03-28
公開日2011-05-25
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies.
J.Med.Chem., 54, 2011
3SR4
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CRYSTAL STRUCTURE OF HUMAN DOT1L IN COMPLEX WITH A SELECTIVE INHIBITOR
分子名称:Histone-lysine N-methyltransferase, H3 lysine-79 specific, (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ...
著者Diao, J., Chen, P., Yao, Y., Prasad, B.V.V., Song, Y.
登録日2011-07-06
公開日2011-10-05
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies.
J.Am.Chem.Soc., 133, 2011
4EF4
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CRYSTAL STRUCTURE OF STING CTD COMPLEX WITH C-DI-GMP
分子名称:Transmembrane protein 173, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION
著者Ouyang, S., Ru, H., Shaw, N., Jiang, Y., Niu, F., Zhu, Y., Qiu, W., Li, Y., Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4EF5
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CRYSTAL STRUCTURE OF STING CTD
分子名称:Transmembrane protein 173
著者Ouyang, S., Ru, H., Shaw, N., Jiang, Y., Niu, F., Zhu, Y., Qiu, W., Li, Y., Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4NOJ
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CRYSTAL STRUCTURE OF THE MATURE FORM OF ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN ACTIVATED AT PH 3.5
分子名称:Legumain
著者Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOK
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CRYSTAL STRUCTURE OF PROENZYME ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN AT PH 7.5
分子名称:Legumain
著者Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOL
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CRYSTAL STRUCTURE OF PROENZYME ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN MUTANT D233A AT PH 7.5
分子名称:Legumain
著者Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOM
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CRYSTAL STRUCTURE OF ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN ACTIVATED AT PH 4.5
分子名称:Legumain
著者Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4QGU
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PROTEIN DOMAIN COMPLEX WITH SSDNA
分子名称:Gamma-interferon-inducible protein 16, DNA (5'-D(P*AP*GP*GP*CP*CP*GP*GP*CP*GP*TP*GP*A)-3')
著者Ni, X., Ru, H., Zhao, L., Shaw, N., Ding, W., Songying, O., Liu, Z.-J.
登録日2014-05-25
公開日2015-06-17
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.545 Å)
主引用文献New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
J Mol Cell Biol, 8, 2016
4Y5U
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TRANSCRIPTION FACTOR
分子名称:Signal transducer and activator of transcription 6, NICKEL (II) ION
著者Li, J., Niu, F., Ouyang, S., Liu, Z.
登録日2015-02-12
公開日2016-02-17
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (2.708 Å)
主引用文献Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
4Y5W
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TRANSCRIPTION FACTOR-DNA COMPLEX
分子名称:Signal transducer and activator of transcription 6, DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*GP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*CP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3')
著者Li, J., Niu, F., Ouyang, S., Liu, Z.
登録日2015-02-12
公開日2016-02-17
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
5D39
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TRANSCRIPTION FACTOR-DNA COMPLEX
分子名称:Signal transducer and activator of transcription 6, DNA (5'-D(P*TP*CP*TP*GP*TP*CP*TP*TP*CP*CP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3'), DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*GP*GP*AP*AP*GP*AP*CP*AP*GP*A)-3')
著者Li, J., Niu, F., Ouyang, S., Liu, Z.
登録日2015-08-06
公開日2016-08-10
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
5H1Y
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CRYSTAL STRUCTURE OF THE DDX41 DEAD DOMAIN IN COMPLEX WITH SO42- AND MG2+
分子名称:Probable ATP-dependent RNA helicase DDX41, SULFATE ION, MAGNESIUM ION
著者Jiang, Y., Ouyang, S., Liu, Z.J.
登録日2016-10-13
公開日2017-01-18
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural and functional analyses of human DDX41 DEAD domain
Protein Cell, 8, 2017
6NZT
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CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH VOXILAPREVIR
分子名称:HCV NS3/4A protease, Voxilaprevir, ZINC ION, ...
著者Appleby, T.C., Taylor, J.G.
登録日2019-02-14
公開日2019-07-10
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Bioorg.Med.Chem.Lett., 29, 2019
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