Author results

4NHA
  • Download 4nha
  • View 4nha
Molmil generated image of 4nha
STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 16-MER SIRNA HAVING 5'-P AND UU-3' ENDS (3.4 ANGSTROM RESOLUTION)
分子名称:Endoribonuclease Dicer, 5'-R(P*GP*CP*GP*UP*UP*GP*GP*CP*CP*AP*AP*CP*GP*CP*UP*U)-3'
著者Simanshu, D.K., Tian, Y., Ma, J.-B., Patel, D.J.
登録日2013-11-04
公開日2014-03-05
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.401 Å)
主引用文献A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NT1
  • Download 4nt1
  • View 4nt1
Molmil generated image of 4nt1
CRYSTAL STRUCTURE OF APO-FORM OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) AT 1.8 ANGSTROM RESOLUTION
分子名称:accelerated-cell-death 11, SODIUM ION
著者Simanshu, D.K., Brown, R.E., Patel, D.J.
登録日2013-11-29
公開日2014-02-05
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NT2
  • Download 4nt2
  • View 4nt2
Molmil generated image of 4nt2
CRYSTAL STRUCTURE OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH LYSO-SPHINGOMYELIN (D18:1) AT 2.4 ANGSTROM RESOLUTION
分子名称:accelerated-cell-death 11, 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, SULFATE ION, ...
著者Simanshu, D.K., Brown, R.E., Patel, D.J.
登録日2013-11-29
公開日2014-02-05
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NTG
  • Download 4ntg
  • View 4ntg
Molmil generated image of 4ntg
CRYSTAL STRUCTURE OF D60A MUTANT OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH C12 CERAMIDE-1-PHOSPHATE (D18:1/12:0) AT 2.55 ANGSTROM RESOLUTION
分子名称:accelerated-cell-death 11, (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
著者Simanshu, D.K., Brown, R.E., Patel, D.J.
登録日2013-12-02
公開日2014-02-05
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.5505 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NTI
  • Download 4nti
  • View 4nti
Molmil generated image of 4nti
CRYSTAL STRUCTURE OF D60N MUTANT OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH C12 CERAMIDE-1-PHOSPHATE (D18:1/12:0) AT 2.9 ANGSTROM RESOLUTION
分子名称:accelerated-cell-death 11, (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER
著者Simanshu, D.K., Brown, R.E., Patel, D.J.
登録日2013-12-02
公開日2014-02-05
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NTO
  • Download 4nto
  • View 4nto
Molmil generated image of 4nto
CRYSTAL STRUCTURE OF D60A MUTANT OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH C2 CERAMIDE-1-PHOSPHATE (D18:1/2:0) AT 2.15 ANGSTROM RESOLUTION
分子名称:accelerated-cell-death 11, (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER
著者Simanshu, D.K., Brown, R.E., Patel, D.J.
登録日2013-12-02
公開日2014-02-05
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4ONJ
  • Download 4onj
  • View 4onj
Molmil generated image of 4onj
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF NTDRM
分子名称:DNA methyltransferase, SINEFUNGIN
著者Du, J., Patel, D.J.
登録日2014-01-28
公開日2014-06-04
実験手法X-RAY DIFFRACTION (2.807 Å)
主引用文献Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
4ONQ
  • Download 4onq
  • View 4onq
Molmil generated image of 4onq
CRYSTAL STRUCTURE OF NTDRM E283S/R309S/F310S/Y590S/D591S MUTANT
分子名称:DNA methyltransferase, SINEFUNGIN
著者Du, J., Patel, D.J.
登録日2014-01-28
公開日2014-06-04
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
4QBQ
  • Download 4qbq
  • View 4qbq
Molmil generated image of 4qbq
CRYSTAL STRUCTURE OF DNMT3A ADD DOMAIN BOUND TO H3 PEPTIDE
分子名称:DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
著者Li, H., Patel, D.J.
登録日2014-05-08
公開日2015-05-13
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
4QEN
  • Download 4qen
  • View 4qen
Molmil generated image of 4qen
CRYSTAL STRUCTURE OF KRYPTONITE IN COMPLEX WITH MCHH DNA AND SAH
分子名称:Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4, DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*TP*CP*AP*GP*TP*AP*T)-3'), ...
著者Du, J., Li, S., Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4QEO
  • Download 4qeo
  • View 4qeo
Molmil generated image of 4qeo
CRYSTAL STRUCTURE OF KRYPTONITE IN COMPLEX WITH MCHH DNA, H3(1-15) PEPTIDE AND SAH
分子名称:Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4, DNA 5'-GGTACT(5CM)ATCAGTAT-3', ...
著者Du, J., Li, S., Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4QEP
  • Download 4qep
  • View 4qep
Molmil generated image of 4qep
CRYSTAL STRUCTURE OF KRYPTONITE IN COMPLEX WITH MCHG DNA AND SAH
分子名称:Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4, DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*TP*AP*T)-3'), ...
著者Du, J., Li, S., Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4QLM
  • Download 4qlm
  • View 4qlm
Molmil generated image of 4qlm
YDAO RIBOSWITCH BINDING TO C-DI-AMP
分子名称:RNA (108-MER), MAGNESIUM ION, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ...
著者Ren, A.M., Patel, D.J.
登録日2014-06-12
公開日2014-08-13
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.721 Å)
主引用文献c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.
Nat.Chem.Biol., 10, 2014
4QLN
  • Download 4qln
  • View 4qln
Molmil generated image of 4qln
STRUCTURE OF YDAO RIBOSWITCH BINDING WITH C-DI-DAMP
分子名称:RNA (117-MER), (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION
著者Ren, A.M., Patel, D.J.
登録日2014-06-12
公開日2014-08-13
最終更新日2014-09-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.
Nat.Chem.Biol., 10, 2014
4QWN
  • Download 4qwn
  • View 4qwn
Molmil generated image of 4qwn
HISTONE DEMETHYLASE KDM2A-H3K36ME1-ALPHA-KG COMPLEX STRUCTURE
分子名称:Lysine-specific demethylase 2A, Histone H3.2, 2-OXOGLUTARIC ACID, ...
著者Cheng, Z.J., Patel, D.J.
登録日2014-07-16
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QX7
  • Download 4qx7
  • View 4qx7
Molmil generated image of 4qx7
CRYSTAL STRUCTURE OF HISTONE DEMETHYLASE KDM2A-H3K36ME2 WITH ALPHA-KG
分子名称:Lysine-specific demethylase 2A, Histone H3.2, 2-OXOGLUTARIC ACID, ...
著者Cheng, Z.J., Patel, D.J.
登録日2014-07-18
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QX8
  • Download 4qx8
  • View 4qx8
Molmil generated image of 4qx8
CRYSTAL STRUCTURE OF HISTONE DEMETHYLASE KDM2A-H3K36ME3 COMPLEX WITH ALPHA-KG
分子名称:Lysine-specific demethylase 2A, Histone H3.2, NICKEL (II) ION, ...
著者Cheng, Z.J., Patel, D.J.
登録日2014-07-19
公開日2014-11-05
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXB
  • Download 4qxb
  • View 4qxb
Molmil generated image of 4qxb
CRYSTAL STRUCTURE OF HISTONE DEMETHYLASE KDM2A-H3K36ME3 WITH NOG
分子名称:Lysine-specific demethylase 2A, Histone H3.2, N-OXALYLGLYCINE, ...
著者Cheng, Z.J., Patel, D.J.
登録日2014-07-19
公開日2014-11-05
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXC
  • Download 4qxc
  • View 4qxc
Molmil generated image of 4qxc
CRYSTAL STRUCTURE OF HISTONE DEMETHYLASE KDM2A-H3K36ME2 WITH NOG
分子名称:Lysine-specific demethylase 2A, Histone H3.2, N-OXALYLGLYCINE, ...
著者Cheng, Z.J., Patel, D.J.
登録日2014-07-19
公開日2014-11-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXH
  • Download 4qxh
  • View 4qxh
Molmil generated image of 4qxh
CRYSTAL STRUCTURE OF HISTONE DEMETHYLASE KDM2A-H3K36ME1 WITH NOG
分子名称:Lysine-specific demethylase 2A, Histone H3.2, N-OXALYLGLYCINE, ...
著者Cheng, Z.J., Patel, D.J.
登録日2014-07-20
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXO
  • Download 4qxo
  • View 4qxo
Molmil generated image of 4qxo
CRYSTAL STRUCTURE OF HSTING(GROUP2) IN COMPLEX WITH DMXAA
分子名称:Stimulator of interferon genes protein, (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
著者Gao, P., Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QXP
  • Download 4qxp
  • View 4qxp
Molmil generated image of 4qxp
CRYSTAL STRUCTURE OF HSTING(G230I) IN COMPLEX WITH DMXAA
分子名称:Stimulator of interferon genes protein, (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
著者Gao, P., Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QXQ
  • Download 4qxq
  • View 4qxq
Molmil generated image of 4qxq
CRYSTAL STRUCTURE OF HSTING(S162A/Q266I) IN COMPLEX WITH DMXAA
分子名称:Stimulator of interferon genes protein, (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION
著者Gao, P., Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QXR
  • Download 4qxr
  • View 4qxr
Molmil generated image of 4qxr
CRYSTAL STRUCTURE OF HSTING(S162A/G230I/Q266I) IN COMPLEX WITH DMXAA
分子名称:Stimulator of interferon genes protein, (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION
著者Gao, P., Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4YAZ
  • Download 4yaz
  • View 4yaz
Molmil generated image of 4yaz
3',3'-CGAMP RIBOSWITCH BOUND WITH 3',3'-CGAMP
分子名称:RNA (84-MER), MAGNESIUM ION, POTASSIUM ION, ...
著者Ren, A.M., Patel, D.J., Rajashankar, R.K.
登録日2015-02-18
公開日2015-04-15
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015