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4K97
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STRUCTURE OF TERNARY COMPLEX OF CGAS WITH DSDNA AND BOUND ATP
Descriptor:Cyclic GMP-AMP synthase, DNA-F, DNA-R, ...
Authors:Gao, P., Wu, Y., Patel, D.J.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
4K98
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STRUCTURE OF TERNARY COMPLEX OF CGAS WITH DSDNA AND BOUND 5 -PPPG(2 ,5 )PG
Descriptor:Cyclic GMP-AMP synthase, DNA-F, DNA-R, ...
Authors:Gao, P., Wu, Y., Patel, D.J.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
4K99
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STRUCTURE OF TERNARY COMPLEX OF CGAS WITH DSDNA AND BOUND 5 -PPPDG(2 ,5 )PDG
Descriptor:Cyclic GMP-AMP synthase, DNA-F, DNA-R, ...
Authors:Gao, P., Wu, Y., Patel, D.J.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
4K9A
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STRUCTURE OF TERNARY COMPLEX OF CGAS WITH DSDNA AND BOUND 5 -PG(2 ,5 )PA
Descriptor:Cyclic GMP-AMP synthase, DNA-F, DNA-R, ...
Authors:Gao, P., Wu, Y., Patel, D.J.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.264 Å)
Cite:Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
4K9B
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STRUCTURE OF TERNARY COMPLEX OF CGAS WITH DSDNA AND BOUND C[G(2 ,5 )PA(3 ,5 )P]
Descriptor:Cyclic GMP-AMP synthase, DNA-F, DNA-R, ...
Authors:Gao, P., Wu, Y., Patel, D.J.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
4KBR
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CRYSTAL STRUCTURE OF MOUSE CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (APO-FORM)
Descriptor:Glycolipid transfer protein domain-containing protein 1, PHOSPHATE ION
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-23
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4KBS
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 12:0 PHOSPHATIDIC ACID (12:0 PA)
Descriptor:Glycolipid transfer protein domain-containing protein 1, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-23
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4KF6
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 8:0 CERAMIDE-1-PHOSPHATE (8:0-C1P)
Descriptor:Glycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-3-hydroxy-2-(octanoylamino)octadec-4-en-1-yl dihydrogen phosphate
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-26
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (3.195 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4KXT
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STRUCTURE OF HUMAN ARGONAUTE1 IN COMPLEX WITH GUIDE RNA
Descriptor:Protein argonaute-1, RNA
Authors:Nakanishi, K., Patel, D.J.
Deposit date:2013-05-28
Release date:2013-07-31
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity.
Cell Rep, 3, 2013
4LOH
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CRYSTAL STRUCTURE OF HSTING(H232) IN COMPLEX WITH C[G(2',5')PA(3',5')P]
Descriptor:Stimulator of interferon genes protein, cGAMP
Authors:Gao, P., Patel, D.J.
Deposit date:2013-07-12
Release date:2013-08-14
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
4LOI
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CRYSTAL STRUCTURE OF HSTING(H232) IN COMPLEX WITH C[G(2',5')PA(2',5')P]
Descriptor:Stimulator of interferon genes protein, PHOSPHATE ION, 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one
Authors:Gao, P., Patel, D.J.
Deposit date:2013-07-12
Release date:2013-08-14
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
4LOJ
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CRYSTAL STRUCTURE OF MSTING IN COMPLEX WITH C[G(2',5')PA(3',5')P]
Descriptor:Stimulator of interferon genes protein, cGAMP
Authors:Gao, P., Patel, D.J.
Deposit date:2013-07-12
Release date:2013-08-14
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
4LOK
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CRYSTAL STRUCTURE OF MSTING IN COMPLEX WITH C[G(3',5')PA(3',5')P]
Descriptor:Stimulator of interferon genes protein, 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one
Authors:Gao, P., Patel, D.J.
Deposit date:2013-07-12
Release date:2013-08-14
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
4LOL
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CRYSTAL STRUCTURE OF MSTING IN COMPLEX WITH DMXAA
Descriptor:Stimulator of interferon genes protein, (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
Authors:Gao, P., Patel, D.J.
Deposit date:2013-07-12
Release date:2013-08-21
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
4MDX
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CRYSTAL STRUCTURE OF BACILLUS SUBTILIS MAZF IN COMPLEX WITH RNA
Descriptor:mRNA interferase EndoA, RNA, mRNA, ...
Authors:Simanshu, D.K., Patel, D.J.
Deposit date:2013-08-23
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of mRNA Recognition and Cleavage by Toxin MazF and Its Regulation by Antitoxin MazE in Bacillus subtilis.
Mol.Cell, 52, 2013
4ME7
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CRYSTAL STRUCTURE OF BACILLUS SUBTILIS TOXIN MAZF IN COMPLEX WITH COGNATE ANTITOXIN MAZE
Descriptor:mRNA interferase EndoA, Antitoxin EndoAI
Authors:Simanshu, D.K., Patel, D.J.
Deposit date:2013-08-25
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.918 Å)
Cite:Structural Basis of mRNA Recognition and Cleavage by Toxin MazF and Its Regulation by Antitoxin MazE in Bacillus subtilis.
Mol.Cell, 52, 2013
4NGB
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 12-MER SIRNA HAVING UU-3' ENDS (2.25 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3'
Authors:Simanshu, D.K., Tian, Y., Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGC
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 12-MER SIRNA HAVING UA-3' ENDS (2.1 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*A)-3'
Authors:Simanshu, D.K., Tian, Y., Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGD
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 12-MER SIRNA HAVING 5'-P AND UU-3' ENDS (1.95 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(P*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', SULFATE ION, ...
Authors:Tian, Y., Simanshu, D.K., Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.958 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGF
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 17-MER SIRNA HAVING 5'-P AND UU-3' ENDS (3.1 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(P*UP*CP*GP*AP*AP*GP*GP*UP*CP*CP*UP*UP*CP*GP*UP*UP*U)-3'
Authors:Simanshu, D.K., Tian, Y., Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGG
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 13-MER SIRNA HAVING 5'-A AND UU-3' ENDS (2.6 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(*AP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', PHOSPHATE ION
Authors:Simanshu, D.K., Tian, Y., Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH3
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 13-MER SIRNA HAVING 5'-PU AND UU-3' ENDS (2.6 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(P*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3'
Authors:Simanshu, D.K., Tian, Y., Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.616 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH5
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 14-MER SIRNA HAVING 5'-PUU AND UU-3' ENDS (2.55 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(P*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3'
Authors:Tian, Y., Simanshu, D.K., Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH6
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 15-MER SIRNA HAVING 5'-PUUU AND UU-3' ENDS (2.55 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(P*UP*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3'
Authors:Simanshu, D.K., Tian, Y., Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NHA
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STRUCTURE OF HUMAN DICER PLATFORM-PAZ-CONNECTOR HELIX CASSETTE IN COMPLEX WITH 16-MER SIRNA HAVING 5'-P AND UU-3' ENDS (3.4 ANGSTROM RESOLUTION)
Descriptor:Endoribonuclease Dicer, 5'-R(P*GP*CP*GP*UP*UP*GP*GP*CP*CP*AP*AP*CP*GP*CP*UP*U)-3'
Authors:Simanshu, D.K., Tian, Y., Ma, J.-B., Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014