2Q3F | | X-RAY CRYSTAL STRUCTURE OF PUTATIVE HUMAN RAS-RELATED GTP BINDING D IN COMPLEX WITH GMPPNP | | Descriptor: | Ras-related GTP-binding protein D, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Mulichak, A.M., Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Keefe, L.J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-30 | | Release date: | 2007-06-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of human Ras-related GTP-binding D.
To be published
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3MSE | | CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PF110239. | | Descriptor: | Calcium-dependent protein kinase, putative, CALCIUM ION, ... | | Authors: | Wernimont, A.K., Artz, J.D., Hutchinson, A., Sullivan, H., Weadge, J., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Lin, Y.H., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC) | | Deposit date: | 2010-04-29 | | Release date: | 2010-06-23 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of C-terminal domain of PF110239
To be Published
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3OZ6 | | CRYSTAL STRUCTURE OF MAPK FROM CRYPTOSPORIDIUM PARVUM, CGD2_1960 | | Descriptor: | Mitogen-activated protein kinase 1, serine/threonine protein kinase, GLYCEROL | | Authors: | Wernimont, A.K., Lew, J., Lin, Y.H., Sullivan, H., Hassanali, A., Kozieradzki, I., Cossar, D., Arrowsmith, C.H., Bochkarev, A., Bountra, C., Edwards, A.M., Weigelt, J., Hui, R., Neculai, A.M., Hutchinson, A., Structural Genomics Consortium (SGC) | | Deposit date: | 2010-09-24 | | Release date: | 2010-12-08 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960
To be Published
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3P1W | | CRYSTAL STRUCTURE OF RAB GDI FROM PLASMODIUM FALCIPARUM, PFL2060C | | Descriptor: | RabGDI protein | | Authors: | Wernimont, A.K., Neculai, A.M., Weadge, J., MacKenzie, F., Cossar, D., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Langsley, G., Bosch, J., Hui, R., Pizzaro, J.C., Hutchinson, A., Structural Genomics Consortium (SGC) | | Deposit date: | 2010-09-30 | | Release date: | 2010-12-15 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structure of RAB GDI from Plasmodium Falciparum, PFL2060c
To be published
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3Q5I | | CRYSTAL STRUCTURE OF PBANKA_031420 | | Descriptor: | Protein kinase, CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Wernimont, A.K., Hutchinson, A., Sullivan, H., Panico, E., Crombet, L., Cossar, D., Hassani, A., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC) | | Deposit date: | 2010-12-28 | | Release date: | 2011-06-01 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of CDPK1 from Plasmodium Bergheii, PBANKA_031420
To be Published
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5FET | | CRYSTAL STRUCTURE OF PVX_084705 IN PRESENCE OF COMPOUND 2 | | Descriptor: | cGMP-dependent protein kinase, putative, 4-[7-[(dimethylamino)methyl]-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-amine | | Authors: | Wernimont, A.K., Tempel, W., Walker, J.R., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC) | | Deposit date: | 2015-12-17 | | Release date: | 2016-01-13 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.07 Å) | | Cite: | Crystal Structure of PVX_084705 in presence of Compound 2
To be published
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5OCH | | THE CRYSTAL STRUCTURE OF HUMAN ABCB8 IN AN OUTWARD-FACING STATE | | Descriptor: | ATP-binding cassette sub-family B member 8, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Faust, B., Pike, A.C.W., Shintre, C.A., Quiqley, A.M., Chu, A., Barr, A., Shrestha, L., Mukhopadhyay, S., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2017-06-30 | | Release date: | 2018-07-25 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | The crystal structure of human ABCB8 in an outward-facing state
To Be Published
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1HV2 | | SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE | | Descriptor: | ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR | | Authors: | Botuyan, M.V., Mer, G., Yi, G.-S., Koth, C.M., Case, D.A., Edwards, A.M., Chazin, W.J., Arrowsmith, C.H. | | Deposit date: | 2001-01-05 | | Release date: | 2001-09-06 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
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1QUQ | | COMPLEX OF REPLICATION PROTEIN A SUBUNITS RPA14 AND RPA32 | | Descriptor: | PROTEIN (REPLICATION PROTEIN A 32 KD SUBUNIT), PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT) | | Authors: | Bochkarev, A., Bochkareva, E., Frappier, L., Edwards, A.M. | | Deposit date: | 1999-07-02 | | Release date: | 1999-08-13 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding.
EMBO J., 18, 1999
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6CNH | | HUMAN PRPF4B IN COMPLEX WITH REBASTINIB | | Descriptor: | Serine/threonine-protein kinase PRP4 homolog, 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, SULFATE ION | | Authors: | Godoi, P.H.C., Santiago, A.S., Ramos, P.Z., Fala, A.M., Salmazo, A.P.T., Counago, R.M., Righetto, G.L., Silva, P.N.B., Gileadi, O., Guimaraes, C.R.W., Massirer, K.B., Arruda, P., Elkins, J.M., Edwards, A.M., Structural Genomics Consortium (SGC) | | Deposit date: | 2018-03-08 | | Release date: | 2018-03-28 | | Last modified: | 2019-04-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the human PRPF4B in complex with Rebastinib
To be Published
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1DPU | | SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN RPA32 COMPLEXED WITH UNG2(73-88) | | Descriptor: | REPLICATION PROTEIN A (RPA32) C-TERMINAL DOMAIN, URACIL DNA GLYCOSYLASE (UNG2) | | Authors: | Mer, G., Edwards, A.M., Chazin, W.J. | | Deposit date: | 1999-12-27 | | Release date: | 2000-11-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA.
Cell(Cambridge,Mass.), 103, 2000
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1EF4 | | SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | | Descriptor: | DNA-DIRECTED RNA POLYMERASE, ZINC ION | | Authors: | Mackereth, C.D., Arrowsmith, C.H., Edwards, A.M., Mcintosh, L.P., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-02-07 | | Release date: | 2000-06-14 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1EIJ | | NMR ENSEMBLE OF METHANOBACTERIUM THERMOAUTOTROPHICUM PROTEIN 1615 | | Descriptor: | HYPOTHETICAL PROTEIN MTH1615 | | Authors: | Christendat, D., Booth, V., Gernstein, M., Arrowsmith, C.H., Edwards, A.M., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-02-25 | | Release date: | 2000-11-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structural proteomics of an archaeon.
Nat.Struct.Biol., 7, 2000
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1EIK | | SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT RPB5 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | | Descriptor: | RNA POLYMERASE SUBUNIT RPB5 | | Authors: | Yee, A., Booth, V., Dharamsi, A., Engel, A., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-02-25 | | Release date: | 2000-06-21 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1EJ2 | | CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE WITH BOUND NAD+ | | Descriptor: | NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, SULFATE ION, SODIUM ION, ... | | Authors: | Saridakis, V., Christendat, D., Kimber, M.S., Edwards, A.M., Pai, E.F., Midwest Center for Structural Genomics (MCSG), Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-02-29 | | Release date: | 2001-03-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
J.Biol.Chem., 276, 2001
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1EJE | | CRYSTAL STRUCTURE OF AN FMN-BINDING PROTEIN | | Descriptor: | FMN-BINDING PROTEIN, NICKEL (II) ION, SULFATE ION, ... | | Authors: | Christendat, D., Saridakis, V., Bochkarev, A., Arrowsmith, C., Edwards, A.M., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-03-02 | | Release date: | 2000-10-11 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural proteomics of an archaeon.
Nat.Struct.Biol., 7, 2000
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1ENW | |
1EO0 | | CONSERVED DOMAIN COMMON TO TRANSCRIPTION FACTORS TFIIS, ELONGIN A, CRSP70 | | Descriptor: | TRANSCRIPTION ELONGATION FACTOR S-II | | Authors: | Booth, V., Koth, C., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-03-21 | | Release date: | 2000-05-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70
J.Biol.Chem., 275, 2000
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1EP0 | | HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | | Descriptor: | DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE | | Authors: | Christendat, D., Saridakis, V., Bochkarev, A., Pai, E.F., Arrowsmith, C.H., Edwards, A.M., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-03-24 | | Release date: | 2000-12-13 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.
J.Biol.Chem., 275, 2000
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1EPZ | | CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOASE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM WITH BOUND LIGAND. | | Descriptor: | DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE, THYMIDINE-5'-DIPHOSPHATE | | Authors: | Christendat, D., Saridakis, V., Bochkarev, A., Pai, E.F., Arrowsmith, C., Edwards, A.M. | | Deposit date: | 2000-03-30 | | Release date: | 2000-12-13 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.
J.Biol.Chem., 275, 2000
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1HYB | | CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE | | Descriptor: | NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | | Authors: | Saridakis, V., Christendat, D., Kimber, M.S., Edwards, A.M., Pai, E.F. | | Deposit date: | 2001-01-18 | | Release date: | 2001-03-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
J.Biol.Chem., 276, 2001
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1IIO | |
1JW2 | | SOLUTION STRUCTURE OF HEMOLYSIN EXPRESSION MODULATING PROTEIN HHA FROM ESCHERICHIA COLI. ONTARIO CENTRE FOR STRUCTURAL PROTEOMICS TARGET EC0308_1_72; NORTHEAST STRUCTURAL GENOMICS TARGET ET88 | | Descriptor: | HEMOLYSIN EXPRESSION MODULATING PROTEIN Hha | | Authors: | Chang, X., Yee, A., Savchenko, A., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2001-09-02 | | Release date: | 2002-02-27 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | An NMR approach to structural proteomics
Proc.Natl.Acad.Sci.USA, 99, 2002
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1JW3 | | SOLUTION STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM PROTEIN 1598. ONTARIO CENTRE FOR STRUCTURAL PROTEOMICS TARGET MTH1598_1_140; NORTHEAST STRUCTURAL GENOMICS TARGET TT6 | | Descriptor: | Conserved Hypothetical Protein MTH1598 | | Authors: | Chang, X., Connelly, G., Yee, A., Kennedy, M.A., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2001-09-02 | | Release date: | 2002-02-27 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | An NMR approach to structural proteomics.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1K3R | | CRYSTAL STRUCTURE OF THE METHYLTRANSFERASE WITH A KNOT FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | | Descriptor: | conserved protein MT0001 | | Authors: | Zarembinski, T.I., Kim, Y., Peterson, K., Christendat, D., Dharamsi, A., Arrowsmith, C.H., Edwards, A.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-10-03 | | Release date: | 2002-05-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Deep trefoil knot implicated in RNA binding found in an archaebacterial protein.
Proteins, 50, 2003
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