9O0X

Co-crystal structure of human TREX1 in complex with an inhibitor

This is a non-PDB format compatible entry.

Summary for 9O0X

• Entry DOI: 10.2210/pdb9o0x/pdb
• Descriptor: Three-prime repair exonuclease 1, 5-({N-[(2,3-dichlorophenyl)methyl]-3,5-difluorobenzamido}methyl)-3-(methylamino)pyridine-2-carboxylic acid, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: trex1, sgc, transport protein, structural genomics, psi-biology, structural genomics consortium, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 77271.65

Authors

Dehghani-Tafti, S.,Dong, A.,Li, Y.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2025-04-03, release date: 2025-05-21)

• Primary citation: Dehghani-Tafti, S.,Dong, A.,Li, Y.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC); Co-crystal structure of human TREX1 in complex with an inhibitor; To be published,

Experimental method

X-RAY DIFFRACTION (1.68 Å)