7NNS

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Momelotinib

Summary for 7NNS

• Entry DOI: 10.2210/pdb7nns/pdb
• Descriptor: Activin receptor type I, 1,2-ETHANEDIOL, Momelotinib, ... (5 entities in total)
• Functional Keywords: kinase, bmp, inhibitor, signalling, signaling protein
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 35996.94

Authors

Williams, E.,Chen, Z.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (deposition date: 2021-02-25, release date: 2021-04-07, Last modification date: 2024-01-31)

• Primary citation: Williams, E.,Chen, Z.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Momelotinib; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.14 Å)