6I81

Crystal Structure of the second bromodomain of BRD2 in complex with RT56

Summary for 6I81

• Entry DOI: 10.2210/pdb6i81/pdb
• Descriptor: Bromodomain-containing protein 2, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: bet, bromodomain, rt56, inhibitor, structural genomics, structural genomics consortium, sgc, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 13859.42

Authors

Picaud, S.,Traquete, R.,Bernardes, G.J.L.,Newman, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Filippakopoulos, P.,Structural Genomics Consortium (SGC) (deposition date: 2018-11-19, release date: 2019-11-27, Last modification date: 2024-01-24)

• Primary citation: Picaud, S.,Traquete, R.,Bernardes, G.J.L.,Newman, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Filippakopoulos, P.,Structural Genomics Consortium (SGC); Crystal Structure of the second bromodomain of BRD2 in complex with RT56; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)