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5WUX
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BU of 5wux by Molmil
TNFalpha-certolizumab Fab
Descriptor: Tumor necrosis factor alpha, heavy, light
Authors:Heo, Y.S, Lee, J.U.
Deposit date:2016-12-21
Release date:2017-06-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
5WUV
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BU of 5wuv by Molmil
Crystal structure of Certolizumab Fab
Descriptor: heavy chain, light chain
Authors:Heo, Y.S, Lee, J.U, Son, J.Y, Shin, W, Yoo, K.Y.
Deposit date:2016-12-21
Release date:2017-06-07
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
4Y7I
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BU of 4y7i by Molmil
Crystal Structure of MTMR8
Descriptor: Myotubularin-related protein 8, PHOSPHATE ION
Authors:Yoo, K, Lee, J, Son, J, Shin, W, Im, D, Heo, Y.S.
Deposit date:2015-02-15
Release date:2015-07-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structure of the catalytic phosphatase domain of MTMR8: implications for dimerization, membrane association and reversible oxidation.
Acta Crystallogr.,Sect.D, 71, 2015
5GGU
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BU of 5ggu by Molmil
Crystal structure of tremelimumab Fab
Descriptor: heavy chain, light chain
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGS
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BU of 5ggs by Molmil
PD-1 in complex with pembrolizumab Fab
Descriptor: Programmed cell death protein 1, heavy chain, light chain
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGV
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BU of 5ggv by Molmil
CTLA-4 in complex with tremelimumab Fab
Descriptor: Cytotoxic T-lymphocyte protein 4, heavy chain, light chain
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGT
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BU of 5ggt by Molmil
PD-L1 in complex with BMS-936559 Fab
Descriptor: IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5Y9J
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BU of 5y9j by Molmil
BAFF in complex with belimumab
Descriptor: Tumor necrosis factor ligand superfamily member 13B, belibumab light chain, belimumab heavy chain
Authors:Heo, Y.-S, Shin, W.
Deposit date:2017-08-25
Release date:2018-02-21
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
5GGR
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BU of 5ggr by Molmil
PD-1 in complex with nivolumab Fab
Descriptor: Programmed cell death protein 1, heavy chain, light chain
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGQ
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BU of 5ggq by Molmil
Crystal structure of Nivolumab Fab fragment
Descriptor: nivolumab heavy chain, nivolumab light chain
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5Y9K
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BU of 5y9k by Molmil
Structure of the belimumab Fab fragment
Descriptor: belimumab heavy chain, belimumab light chain
Authors:Heo, Y.-S, Shin, W.
Deposit date:2017-08-25
Release date:2018-02-21
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018

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