1QSJ
 
 | | N-TERMINALLY TRUNCATED C3DG FRAGMENT | | Descriptor: | COMPLEMENT C3 PRECURSOR | | Authors: | Zanotti, G, Bassetto, A, Battistutta, R, Stoppini, M, Folli, C, Berni, R. | | Deposit date: | 1999-06-22 | | Release date: | 2000-07-31 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochim.Biophys.Acta, 1478, 2000
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3Q1E
 | | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | | Authors: | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | | Deposit date: | 2010-12-17 | | Release date: | 2011-05-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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1BOH
 | | SULFUR-SUBSTITUTED RHODANESE (ORTHORHOMBIC FORM) | | Descriptor: | RHODANESE | | Authors: | Gliubich, F, Berni, R, Cianci, M, Trevino, R.J, Horowitz, P.M, Zanotti, G. | | Deposit date: | 1998-08-04 | | Release date: | 1999-04-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions.
J.Biol.Chem., 274, 1999
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1AQB
 | | RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA | | Descriptor: | CADMIUM ION, RETINOL, RETINOL-BINDING PROTEIN | | Authors: | Zanotti, G, Panzalorto, M, Marcato, A, Malpeli, G, Folli, C, Berni, R. | | Deposit date: | 1997-07-28 | | Release date: | 1998-01-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of pig plasma retinol-binding protein at 1.65 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
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3BSZ
 | | Crystal structure of the transthyretin-retinol binding protein-Fab complex | | Descriptor: | Fab fragment heavy chain, Fab fragment light chain, Plasma retinol-binding protein, ... | | Authors: | Zanotti, G, Cendron, L, Gliubich, F, Folli, C, Berni, R. | | Deposit date: | 2007-12-27 | | Release date: | 2008-11-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.38 Å) | | Cite: | Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein.
Febs J., 275, 2008
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3BT0
 | | Crystal structure of transthyretin variant V20S | | Descriptor: | Transthyretin | | Authors: | Zanotti, G, Folli, C, Cendron, L, Gliubich, F, Negro, A, Berni, R. | | Deposit date: | 2007-12-27 | | Release date: | 2008-11-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein.
Febs J., 275, 2008
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4I89
 | | Crystal structure of transthyretin in complex with diflunisal at acidic pH | | Descriptor: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | Deposit date: | 2012-12-03 | | Release date: | 2013-06-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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4I87
 | | Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH | | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | Deposit date: | 2012-12-03 | | Release date: | 2013-06-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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4I85
 | | Crystal structure of transthyretin in complex with CHF5074 at neutral pH | | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | Deposit date: | 2012-12-03 | | Release date: | 2013-06-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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1TYR
 | | TRANSTHYRETIN COMPLEX WITH RETINOIC ACID | | Descriptor: | (9cis)-retinoic acid, TRANSTHYRETIN | | Authors: | Zanotti, G, D'Acunto, M.R, Malpeli, G, Folli, C, Berni, R. | | Deposit date: | 1995-05-12 | | Release date: | 1995-09-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the transthyretin--retinoic-acid complex
Eur.J.Biochem., 234, 1995
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5CR1
 | | Crystal structure of TTR/resveratrol/T4 complex | | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, RESVERATROL, Transthyretin | | Authors: | Zanotti, G, Florio, P, Folli, C, Cianci, M, Del Rio, D, Berni, R. | | Deposit date: | 2015-07-22 | | Release date: | 2015-10-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.545 Å) | | Cite: | Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites.
J.Biol.Chem., 290, 2015
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5M98
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3IWV
 | | Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP) | | Descriptor: | 5-hydroxyisourate hydrolase | | Authors: | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | | Deposit date: | 2009-09-03 | | Release date: | 2010-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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3IWU
 | | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase | | Descriptor: | 5-hydroxyisourate hydrolase | | Authors: | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | | Deposit date: | 2009-09-03 | | Release date: | 2010-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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1FEN
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | ALL-TRANS AXEROPHTHENE, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1FEL
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1FEM
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | RETINOIC ACID, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1ERB
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4WO0
 | | Crystal structure of transthyretin in complex with apigenin | | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Transthyretin | | Authors: | Zanotti, G, Cianci, M, Folli, C, Berni, R. | | Deposit date: | 2014-10-15 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.339 Å) | | Cite: | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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4WNJ
 | | Crystal structure of Transthyretin-quercetin complex | | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DIMETHYL SULFOXIDE, Transthyretin | | Authors: | Zanotti, G, Cianci, M, Berni, R, Folli, C. | | Deposit date: | 2014-10-13 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.398 Å) | | Cite: | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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4WNS
 | | Crystal structure of Transthyretin complexed with pterostilbene | | Descriptor: | DIMETHYL SULFOXIDE, Pterostilbene, SULFATE ION, ... | | Authors: | Zanotti, G, Cianci, M, Folli, C, Berni, R. | | Deposit date: | 2014-10-14 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.399 Å) | | Cite: | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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1IIU
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2H6U
 | | Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein) | | Descriptor: | 5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN) | | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | | Deposit date: | 2006-06-01 | | Release date: | 2006-10-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
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2H1X
 | | Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | | Descriptor: | 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | | Deposit date: | 2006-05-17 | | Release date: | 2006-10-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
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1BOI
 | | N-TERMINALLY TRUNCATED RHODANESE | | Descriptor: | RHODANESE | | Authors: | Gliubich, F, Berni, R, Cianci, M, Trevino, R.J, Horowitz, P.M, Zanotti, G. | | Deposit date: | 1998-08-04 | | Release date: | 1999-04-27 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions.
J.Biol.Chem., 274, 1999
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