PDB: 593 件ウェブページステータス検索Chemie searchBIRD

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2ECD	Solution structure of the human ABL2 SH2 domain 分子名称: Tyrosine-protein kinase ABL2 著者 Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-13 公開日 2008-02-19 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human ABL2 SH2 domain To be Published
2EOB	Solution structure of the second SH2 domain from rat PLC gamma-2 分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 著者 Sano, R, Hayashi, F, Nagashima, T, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-29 公開日 2008-04-01 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the second SH2 domain from rat PLC gamma-2 To be Published
2EO6	Solution structure of the SH2 domain from mouse B-cell linker protein BLNK 分子名称: B-cell linker protein 著者 Sano, R, Hayashi, F, Kurosaki, C, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-29 公開日 2008-04-01 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain from mouse B-cell linker protein BLNK To be Published
2EYV	SH2 domain of CT10-Regulated Kinase 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2ETZ	The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide 分子名称: Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK 著者 Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. 登録日 2005-10-27 公開日 2006-02-07 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide. J.Mol.Biol., 357, 2006
2EU0	The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide 分子名称: Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK 著者 Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. 登録日 2005-10-27 公開日 2006-02-07 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide. J.Mol.Biol., 357, 2006
2FCI	Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase 分子名称: C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759, Doubly phosphorylated peptide derived from Syk kinase comprising residues 338-350 著者 Groesch, T.D, Zhou, F, Mattila, S, Geahlen, R.L, Post, C.B. 登録日 2005-12-12 公開日 2006-01-31 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase J.Mol.Biol., 356, 2006
2GE9	Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase 分子名称: Tyrosine-protein kinase BTK 著者 Cheng, J.-W, Huang, K.-C. 登録日 2006-03-18 公開日 2006-10-24 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase J.Biomol.Nmr, 36, 2006
2H5K	Crystal Structure of Complex Between the Domain-Swapped Dimeric Grb2 SH2 Domain and Shc-Derived Ligand, Ac-NH-pTyr-Val-Asn-NH2 分子名称: CACODYLATE ION, Growth factor receptor-bound protein 2, Shc-Derived Ligand 著者 Benfield, A.P, Whiddon, B.B, Martin, S.F. 登録日 2006-05-26 公開日 2006-08-15 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462, 2007
2GSB	Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 分子名称: Ras GTPase-activating protein 1 著者 Kurosaki, C, Suetake, T, Yoshida, M, Hayashi, F, Yokoyma, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-26 公開日 2007-05-01 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 To be Published
2H46	Native domain-swapped dimer crystal structure of the Grb2 SH2 domain 分子名称: GLYCEROL, Growth Receptor Binding Protein 2 著者 Benfield, A.P, Martin, S.F, Whiddon, B.B. 登録日 2006-05-23 公開日 2006-06-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462, 2007
2HDV	Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B 分子名称: SH2-B PH domain containing signaling mediator 1 gamma isoform 著者 Hu, J, Hubbard, S.R. 登録日 2006-06-20 公開日 2006-08-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol., 361, 2006
2HDX	Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide 分子名称: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform 著者 Hu, J, Hubbard, S.R. 登録日 2006-06-21 公開日 2006-08-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol., 361, 2006
2HMH	Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide. 分子名称: Interleukin-6 receptor beta chain, Suppressor of cytokine signaling 3 著者 Bergamin, E, Wu, J, Hubbard, S.R. 登録日 2006-07-11 公開日 2006-08-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3. Structure, 14, 2006
2HUW	X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand 分子名称: Growth factor receptor-bound protein 2, N-({(1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropyl}carbonyl)-L-valyl-L-aspartamide, PHOSPHATE ION 著者 Benfield, A.P, Martin, S.F. 登録日 2006-07-27 公開日 2006-08-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein-Ligand Interactions. Angew.Chem.Int.Ed.Engl., 45, 2006
2IUH	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide 分子名称: C-KIT PHOSPHOTYROSYL PEPTIDE, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2021-04-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2IUG	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2IUI	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with PDGFR phosphotyrosyl peptide 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Platelet-derived growth factor receptor beta 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2021-04-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
1LCJ	SH2 (SRC HOMOLOGY-2) DOMAIN OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 11 RESIDUE PHOSPHOTYROSYL PEPTIDE EPQPYEEIPIYL 分子名称: P56==LCK== TYROSINE KINASE, PHOSPHOPEPTIDE EPQ(PHOSPHO)YEEIPIYL 著者 Eck, M, Harrison, S. 登録日 1994-12-12 公開日 1995-10-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck. Nature, 362, 1993
1LKK	HUMAN P56-LCK TYROSINE KINASE SH2 DOMAIN IN COMPLEX WITH THE PHOSPHOTYROSYL PEPTIDE AC-PTYR-GLU-GLU-ILE (PYEEI PEPTIDE) 分子名称: ACETYL GROUP, HUMAN P56 TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE AC-PTYR-GLU-GLU-ILE 著者 Tong, L. 登録日 1995-11-10 公開日 1996-03-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Crystal structures of the human p56lck SH2 domain in complex with two short phosphotyrosyl peptides at 1.0 A and 1.8 A resolution. J.Mol.Biol., 256, 1996
1LKL	HUMAN P56-LCK TYROSINE KINASE SH2 DOMAIN IN COMPLEX WITH THE PHOSPHOTYROSYL PEPTIDE AC-PTYR-GLU-GLU-GLY (PYEEG PEPTIDE) 分子名称: HUMAN P56 TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE AC-PTYR-GLU-GLU-GLY 著者 Tong, L. 登録日 1995-11-10 公開日 1996-03-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of the human p56lck SH2 domain in complex with two short phosphotyrosyl peptides at 1.0 A and 1.8 A resolution. J.Mol.Biol., 256, 1996
1LUK	NMR Structure of the Itk SH2 domain, Pro287cis, Energy minimized average structure 分子名称: Tyrosine-protein kinase ITK/TSK 著者 Mallis, R.J, Brazin, K.N, Fulton, B.F, Andreotti, A.H. 登録日 2002-05-22 公開日 2002-11-27 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Structural characterization of a proline-driven conformational switch within the Itk SH2 domain Nat.Struct.Biol., 9, 2002
1LUN	NMR Structure of the Itk SH2 domain, Pro287trans, energy minimized average structure 分子名称: Tyrosine-protein kinase ITK/TSK 著者 Mallis, R.J, Brazin, K.N, Fulton, D.B, Andreotti, A.H. 登録日 2002-05-22 公開日 2002-11-27 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Structural characterization of a proline-driven conformational switch within the Itk SH2 domain Nat.Struct.Biol., 9, 2002
1LUI	NMR Structures of Itk SH2 domain, Pro287cis isoform, ensemble of 20 low energy structures 分子名称: Tyrosine-protein kinase ITK/TSK 著者 Mallis, R.J, Brazin, K.N, Fulton, B.F, Andreotti, A.M. 登録日 2002-05-22 公開日 2002-11-27 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Structural characterization of a proline-driven conformational switch within the Itk SH2 domain Nat.Struct.Biol., 9, 2002
1M61	Crystal structure of the apo SH2 domains of ZAP-70 分子名称: PHOSPHATE ION, TYROSINE-PROTEIN KINASE ZAP-70 著者 Folmer, R.H.A, Geschwindner, S, Xue, Y. 登録日 2002-07-11 公開日 2003-07-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem Biochemistry, 41, 2002

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