2H5K
Crystal Structure of Complex Between the Domain-Swapped Dimeric Grb2 SH2 Domain and Shc-Derived Ligand, Ac-NH-pTyr-Val-Asn-NH2
Summary for 2H5K
Entry DOI | 10.2210/pdb2h5k/pdb |
Related | 2H46 |
Descriptor | Growth factor receptor-bound protein 2, Shc-Derived Ligand, CACODYLATE ION, ... (4 entities in total) |
Functional Keywords | domain-swapping, protein-phosphopeptide complex, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P62993 |
Total number of polymer chains | 3 |
Total formula weight | 28010.37 |
Authors | Benfield, A.P.,Whiddon, B.B.,Martin, S.F. (deposition date: 2006-05-26, release date: 2006-08-15, Last modification date: 2017-10-18) |
Primary citation | Benfield, A.P.,Whiddon, B.B.,Clements, J.H.,Martin, S.F. Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462:47-53, 2007 Cited by PubMed: 17466257DOI: 10.1016/j.abb.2007.03.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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