1LUI

NMR Structures of Itk SH2 domain, Pro287cis isoform, ensemble of 20 low energy structures

Summary for 1LUI

• Entry DOI: 10.2210/pdb1lui/pdb
• Related: 1LUK 1LUM 1LUN
• NMR Information: BMRB: 5461
• Descriptor: Tyrosine-protein kinase ITK/TSK (1 entity in total)
• Functional Keywords: sh2 domain, cis/trans isomerization, proline, itk, tsk, t-cell, transferase
• Biological source: Mus musculus (house mouse)
• Cellular location: Cell membrane: Q03526
• Total number of polymer chains: 1
• Total formula weight: 12558.25

Authors

Mallis, R.J.,Brazin, K.N.,Fulton, B.F.,Andreotti, A.M. (deposition date: 2002-05-22, release date: 2002-11-27, Last modification date: 2022-02-23)

• Primary citation: Mallis, R.J.,Brazin, K.N.,Fulton, D.B.,Andreotti, A.H.; Structural characterization of a proline-driven conformational switch within the Itk SH2 domain; Nat.Struct.Biol., 9:900-905, 2002; PubMed: 12402030; DOI: 10.1038/nsb864

Experimental method

SOLUTION NMR