2HDX
Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
Summary for 2HDX
Entry DOI | 10.2210/pdb2hdx/pdb |
Descriptor | SH2-B PH domain containing signaling mediator 1 gamma isoform, Jak2 protein (3 entities in total) |
Functional Keywords | sh2, jak2, phosphotyrosine, adapter protein, signaling protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 12 |
Total formula weight | 81991.82 |
Authors | Hu, J.,Hubbard, S.R. (deposition date: 2006-06-21, release date: 2006-08-08, Last modification date: 2023-11-15) |
Primary citation | Hu, J.,Hubbard, S.R. Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol., 361:69-79, 2006 Cited by PubMed: 16824542DOI: 10.1016/j.jmb.2006.05.070 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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