7POG
 
 | | High-resolution structure of native toxin A from Clostridioides difficile | | Descriptor: | Toxin A, ZINC ION | | Authors: | Boesen, T, Joergensen, R, Aminzadeh, A, Engelbrecht Larsen, C. | | Deposit date: | 2021-09-08 | | Release date: | 2021-12-08 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | High-resolution structure of native toxin A from Clostridioides difficile.
Embo Rep., 23, 2022
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7V1N
 | | Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI | | Descriptor: | Isoform Beta of Tissue factor pathway inhibitor, Toxin B | | Authors: | Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L. | | Deposit date: | 2021-08-05 | | Release date: | 2022-02-23 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile.
Cell, 185, 2022
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7N95
 | | state 1 of TcdB and FZD2 at pH5 | | Descriptor: | Frizzled-2, Toxin B | | Authors: | Jiang, M, Zhang, J. | | Deposit date: | 2021-06-16 | | Release date: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
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7N9Q
 | | State 3 of TcdB and FZD2 at pH5 | | Descriptor: | Toxin B | | Authors: | Jiang, M, Zhang, J. | | Deposit date: | 2021-06-18 | | Release date: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
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7N97
 | | State 2 of TcdB and FZD2 at pH5 | | Descriptor: | Frizzled-2, Toxin B | | Authors: | Jiang, M, Zhang, J. | | Deposit date: | 2021-06-17 | | Release date: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (5.1 Å) | | Cite: | Structural Basis for Receptor Recognition of the Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
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7N9R
 | | state 4 of TcdB and FZD2 at pH5 | | Descriptor: | Toxin B | | Authors: | Jiang, M, Zhang, J. | | Deposit date: | 2021-06-18 | | Release date: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
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7N9S
 | | TcdB and frizzled-2 CRD complex | | Descriptor: | Frizzled-2, Toxin B | | Authors: | Jiang, M, Zhang, J. | | Deposit date: | 2021-06-18 | | Release date: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (5.1 Å) | | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
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7N9Y
 | | Full-length TcdB and CSPG4 (401-560) complex | | Descriptor: | Chondroitin sulfate proteoglycan 4, Toxin B | | Authors: | Jiang, M, Zhang, J. | | Deposit date: | 2021-06-18 | | Release date: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
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7U2P
 | | Structure of TcdA GTD in complex with RhoA | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Glucosyltransferase TcdA, MAGNESIUM ION, ... | | Authors: | Baohua, C, Zheng, L, Kay, P, Rongsheng, J. | | Deposit date: | 2022-02-24 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.596 Å) | | Cite: | Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition.
Sci Rep, 12, 2022
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7SO7
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7SO5
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7UBY
 | | Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3 | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glucosyltransferase TcdA, ... | | Authors: | Chen, B, Rongsheng, J, Kay, P. | | Deposit date: | 2022-03-15 | | Release date: | 2022-11-16 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies.
Front Immunol, 13, 2022
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8X2I
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8X2H
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8JB5
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8QEN
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8JHZ
 | | Cryo-EM structure of the TcsH-TMPRSS2 complex | | Descriptor: | Hemorrhagic toxin, Transmembrane protease serine 2, ZINC ION | | Authors: | Zhou, R, Liang, T, Zhan, X. | | Deposit date: | 2023-05-25 | | Release date: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin.
Nat Commun, 15, 2024
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8QEO
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