7SO5

Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B

Summary for 7SO5

• Entry DOI: 10.2210/pdb7so5/pdb
• Descriptor: Fab B2 HC, Fab B2 LC, Toxin B, ... (4 entities in total)
• Functional Keywords: antibody, toxin, tcdb, epitope, clostridium difficile toxin, toxin-immune system complex, toxin/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 109366.44

Authors

Liu, J. (deposition date: 2021-10-29, release date: 2022-05-11, Last modification date: 2023-10-18)

• Primary citation: Liu, J.,Kothe, M.,Zhang, J.,Oloo, E.,Stegalkina, S.,Mundle, S.T.,Li, L.,Zhang, J.,Cole, L.E.,Barone, L.,Biemann, H.P.,Kleanthous, H.,Anosova, N.G.,Anderson, S.F.; Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B.; Curr Res Struct Biol, 4:96-105, 2022; PubMed: 35469152; DOI: 10.1016/j.crstbi.2022.03.003

Experimental method

X-RAY DIFFRACTION (1.797 Å)