7SO5
Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR203-HIS209 | |
| L | TYR197-HIS203 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0000269|PubMed:31308519, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:2BVM, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN, ECO:0007744|PDB:6OQ7 |
| Chain | Residue | Details |
| A | VAL101 | |
| A | SER269 | |
| A | SER518 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:2BVM, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN |
| Chain | Residue | Details |
| A | ASN139 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:31308519, ECO:0007744|PDB:6OQ5 |
| Chain | Residue | Details |
| A | ASP286 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0000305|PubMed:31308519, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN, ECO:0007744|PDB:5UQT, ECO:0007744|PDB:6OQ7 |
| Chain | Residue | Details |
| A | ASP288 | |
| A | GLU515 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:15632438 |
| Chain | Residue | Details |
| A | LEU543 |
