PDB: 46 件ウェブページステータス検索Chemie searchBIRD

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4XXO	Crystal Structure of Human APOBEC3A 分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION 著者 Bohn, M.F, Shandilya, S.M.D, Schiffer, C.A. 登録日 2015-01-30 公開日 2015-04-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.843 Å) 主引用文献 The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization. Structure, 23, 2015
7UXD	Crystal structure of APOBEC3G Catalytic domain complex with ssDNA containing 2'-deoxy Zebularine. 分子名称: DNA (5'-D(*AP*AP*TP*CP*CP*(DDN)P*AP*AP*A)-3'), DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Maiti, A, Matsuo, H. 登録日 2022-05-05 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state. Nat Commun, 13, 2022
5KEG	Crystal structure of APOBEC3A in complex with a single-stranded DNA 分子名称: CALCIUM ION, CHLORIDE ION, DNA (5'-D(*TP*TP*CP*TP*T)-3'), ... 著者 Kouno, T, Hilbert, B.J, Silvas, T, Royer, W.E, Matsuo, H, Schiffer, C.A. 登録日 2016-06-09 公開日 2017-05-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity. Nat Commun, 8, 2017
3E1U	The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S. 登録日 2008-08-04 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature, 456, 2008
4ROV	The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C. 登録日 2014-10-29 公開日 2014-12-31 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA J.Biol.Chem., 290, 2015
4ROW	The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C. 登録日 2014-10-29 公開日 2014-12-31 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA J.Biol.Chem., 290, 2015
3IR2	Crystal structure of the APOBEC3G catalytic domain 分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3G, MAGNESIUM ION, ... 著者 Shandilya, S.M.D, Schiffer, C.A. 登録日 2009-08-21 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces. Structure, 18, 2010
3IQS	Crystal structure of the anti-viral APOBEC3G catalytic domain 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Holden, L.G, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S. 登録日 2009-08-20 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature, 456, 2008
6K3K	Solution structure of APOBEC3G-CD2 with ssDNA, Product B 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, DNA/RNA (5'-D(*AP*TP*TP*CP*UP*(ICY)P*AP*AP*TP*T)-3'), ZINC ION 著者 Cao, C, Yan, X, Lan, W, Wang, C. 登録日 2019-05-19 公開日 2019-06-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA. Chem Asian J, 14, 2019
6K3J	Solution structure of APOBEC3G-CD2 with ssDNA, Product A 分子名称: DNA (5'-D(*AP*TP*TP*CP*UP*(IUR)P*AP*AP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Cao, C, Yan, X, Lan, W, Wang, C. 登録日 2019-05-19 公開日 2019-06-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA. Chem Asian J, 14, 2019
3V4K	First-In-Class Small Molecule Inhibitors of the Single-strand DNA Cytosine Deaminase APOBEC3G 分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3G, MAGNESIUM ION, ... 著者 Shandilya, S.M.D, Ali, A, Schiffer, C.A. 登録日 2011-12-15 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G. Acs Chem.Biol., 7, 2012
3V4J	First-In-Class Small Molecule Inhibitors of the Single-strand DNA Cytosine Deaminase APOBEC3G 分子名称: 4-[methyl(nitroso)amino]benzene-1,2-diol, DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Shandilya, S.M.D, Ali, A, Schiffer, C.A. 登録日 2011-12-15 公開日 2012-02-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G. Acs Chem.Biol., 7, 2012
6BUX	CRYSTAL STRUCTURE OF APOBEC3G CATALYTIC DOMAIN COMPLEX WITH SUBSTRATE SSDNA 分子名称: Apolipoprotein B mRNA editing enzyme catalytic subunit 3G catalytic domain, DNA (5'-D(*AP*AP*TP*CP*CP*CP*AP*AP*A)-3'), GLYCEROL, ... 著者 Maiti, A, Matsuo, H. 登録日 2017-12-11 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.856 Å) 主引用文献 Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA. Nat Commun, 9, 2018
6NFK	Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G bound to iodide 分子名称: 1,2-ETHANEDIOL, DNA dC->dU-editing enzyme APOBEC-3B, IODIDE ION 著者 Shi, K, Orellana, K, Aihara, H. 登録日 2018-12-20 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B Faseb Bioadv, 2, 2020
6NFM	Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G 分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3B 著者 Shi, K, Aihara, H. 登録日 2018-12-20 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B Faseb Bioadv, 2, 2020
2M65	NMR structure of human restriction factor APOBEC3A 分子名称: Probable DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION 著者 Byeon, I.L, Byeon, C, Ahn, J, Gronenborn, A.M. 登録日 2013-03-21 公開日 2013-05-22 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity. Nat Commun, 4, 2013
6NFL	Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G complexed with 2-HP 分子名称: 1,2-ETHANEDIOL, 1,3-diazinan-2-one, CHLORIDE ION, ... 著者 Shi, K, Orellana, K, Aihara, H. 登録日 2018-12-20 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.731 Å) 主引用文献 Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B Faseb Bioadv, 2, 2020
2NBQ	NMR Structure of the C-Terminal Domain of human APOBEC3B 分子名称: DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION 著者 Byeon, I.L, Byeon, C, Gronenborn, A.M. 登録日 2016-03-09 公開日 2016-06-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity. Biochemistry, 55, 2016
2NYT	The APOBEC2 Crystal Structure and Functional Implications for AID 分子名称: Probable C->U-editing enzyme APOBEC-2, ZINC ION 著者 Prochnow, C, Bransteitter, R, Klein, M, Goodman, M, Chen, X. 登録日 2006-11-21 公開日 2007-01-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The APOBEC-2 crystal structure and functional implications for the deaminase AID. Nature, 445, 2007
7D3V	Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A 分子名称: DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION 著者 Cao, C.Y, Liu, Y.P, Lan, W.X. 登録日 2020-09-21 公開日 2021-10-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3 To Be Published
7D3W	Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A 分子名称: DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION 著者 Cao, C, Liu, Y, Lan, W. 登録日 2020-09-21 公開日 2021-10-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance. Protein Sci., 31, 2022
7D3X	Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A 分子名称: DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION 著者 Cao, C, Liu, Y. 登録日 2020-09-21 公開日 2021-10-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance. Protein Sci., 31, 2022
2JYW	Solution structure of C-terminal domain of APOBEC3G 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Chen, K, Harjes, E, Gross, P.J, Fahmy, A, Lu, Y, Shindo, K, Harris, R.S, Matsuo, H. 登録日 2007-12-20 公開日 2008-02-26 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G. Nature, 452, 2008
2KEM	Extended structure of citidine deaminase domain of APOBEC3G 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Harjes, E, Gross, P.J, Chen, K, Lu, Y, Shindo, K, Nowarski, R, Gross, J.D, Kotler, M, Harris, R.S, Matsuo, H. 登録日 2009-01-30 公開日 2009-06-02 最終更新日 2021-11-10 実験手法 SOLUTION NMR 主引用文献 An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model J.Mol.Biol., 389, 2009
2KBO	Structure, interaction, and real-time monitoring of the enzymatic reaction of wild type APOBEC3G 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION 著者 Furukawa, A, Nagata, T, Matsugami, A, Habu, Y, Sugiyama, R, Hayashi, F, Kobayashi, N, Yokoyama, S, Takaku, H, Katahira, M. 登録日 2008-12-04 公開日 2009-02-03 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G Embo J., 28, 2009

 

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