6NFL

Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G complexed with 2-HP

Summary for 6NFL

Entry DOI	10.2210/pdb6nfl/pdb
Descriptor	DNA dC->dU-editing enzyme APOBEC-3B, 1,3-diazinan-2-one, pyrimidin-2-ol, ... (6 entities in total)
Functional Keywords	apobec, deaminase, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	23262.67
Authors	Shi, K.,Orellana, K.,Aihara, H. (deposition date: 2018-12-20, release date: 2019-12-25, Last modification date: 2023-10-11)
Primary citation	Shi, K.,Demir, O.,Carpenter, M.A.,Banerjee, S.,Harki, D.A.,Amaro, R.E.,Harris, R.S.,Aihara, H. Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B Faseb Bioadv, 2:49-58, 2020 Cited by DOI: 10.1096/fba.2019-00068 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.731 Å)

Structure validation