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6NFM

Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G

Summary for 6NFM
Entry DOI10.2210/pdb6nfm/pdb
DescriptorDNA dC->dU-editing enzyme APOBEC-3B, CHLORIDE ION (3 entities in total)
Functional Keywordsapobec, deaminase, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight22880.26
Authors
Shi, K.,Aihara, H. (deposition date: 2018-12-20, release date: 2019-12-25, Last modification date: 2024-10-23)
Primary citationShi, K.,Demir, O.,Carpenter, M.A.,Banerjee, S.,Harki, D.A.,Amaro, R.E.,Harris, R.S.,Aihara, H.
Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B
Faseb Bioadv, 2:49-58, 2020
Cited by
DOI: 10.1096/fba.2019-00068
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.53 Å)
Structure validation

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