PDB: 492 resultsInfo pagesStatus searchChemie searchBIRD

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3DGQ	Crystal structure of the glutathione transferase PI enzyme in complex with the bifunctional inhibitor, etharapta Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... Authors: Parker, L.J. Deposit date: 2008-06-15 Release date: 2009-04-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Rational design of an organometallic glutathione transferase inhibitor Angew.Chem.Int.Ed.Engl., 48, 2009
3EE2	Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole Descriptor: GLUTATHIONE, Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, ... Authors: Oakley, A.J. Deposit date: 2008-09-04 Release date: 2008-09-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase Eur.J.Med.Chem., 45, 2010
3F63	Crystal structure of a Delta class GST (adGSTD4-4) from Anopheles dirus, in complex with S-hexyl glutathione Descriptor: Glutathione transferase GST1-4, S-HEXYLGLUTATHIONE Authors: Wongsantichon, J, Robinson, R.C, Ketterman, A.J. Deposit date: 2008-11-05 Release date: 2009-10-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural contributions of delta class glutathione transferase active-site residues to catalysis Biochem.J., 428, 2010
3F6D	Crystal Structure of a Genetically Modified Delta Class GST (adGSTD4-4) from Anopheles dirus, F123A, in Complex with S-Hexyl Glutathione Descriptor: Glutathione transferase GST1-4, S-HEXYLGLUTATHIONE Authors: Wongsantichon, J, Robinson, R.C, Ketterman, A.J. Deposit date: 2008-11-05 Release date: 2009-10-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural contributions of delta class glutathione transferase active-site residues to catalysis Biochem.J., 428, 2010
3FRC	Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 Descriptor: Glutathione S-transferase, N-[(4S)-4-ammonio-4-carboxybutanoyl]-S-(4-bromobenzyl)-L-cysteinylglycine Authors: Perbandt, M, Liebau, E, Ricci, G. Deposit date: 2009-01-08 Release date: 2010-01-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 To be Published
3FR9	Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 Descriptor: CHLORIDE ION, GLUTATHIONE, Glutathione S-transferase Authors: Perbandt, M, Liebau, E, Ricci, G. Deposit date: 2009-01-08 Release date: 2010-01-26 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 To be Published
3FR6	Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 Descriptor: Glutathione S-transferase, MAGNESIUM ION Authors: Perbandt, M, Liebau, E, Ricci, G. Deposit date: 2009-01-08 Release date: 2010-01-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 To be Published
3FR3	Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 Descriptor: Glutathione S-transferase, OXIDIZED GLUTATHIONE DISULFIDE Authors: Perbandt, M, Liebau, E, Ricci, G. Deposit date: 2009-01-08 Release date: 2010-01-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 To be Published
3G7I	Crystal structure of a Delta class GST (adGSTD4-4) from Anopheles dirus, with glutathione complexed in one subunit Descriptor: GLUTATHIONE, Glutathione transferase GST1-4 Authors: Wongsantichon, J, Robinson, R.C, Ketterman, A.J. Deposit date: 2009-02-10 Release date: 2010-02-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding Arch.Biochem.Biophys., 521, 2012
3G7J	Crystal Structure of a Genetically Modified Delta Class GST (adGSTD4-4) from Anopheles dirus, Y119E, in Complex with S-Hexyl Glutathione Descriptor: Glutathione transferase GST1-4, S-HEXYLGLUTATHIONE Authors: Wongsantichon, J, Robinson, R.C, Ketterman, A.J. Deposit date: 2009-02-10 Release date: 2010-02-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural contributions of delta class glutathione transferase active-site residues to catalysis Biochem.J., 428, 2010
3GUS	Crystal strcture of human Pi class glutathione S-transferase GSTP1-1 in complex with 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]hexan-1-ol, GLUTATHIONE, ... Authors: Federici, L, Lo Sterzo, C, Di Matteo, A, Scaloni, F, Federici, G, Caccuri, A.M. Deposit date: 2009-03-30 Release date: 2009-10-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases Cancer Res., 69, 2009
3GSS	HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID-GLUTATHIONE CONJUGATE Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE, ... Authors: Oakley, A.J, Rossjohn, J, Parker, M.W. Deposit date: 1996-10-29 Release date: 1997-11-12 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate. Biochemistry, 36, 1997
3HJO	Crystal Structure of Glutathione Transferase Pi Y108V Mutant in Complex with the Glutathione Conjugate of Ethacrynic Acid Descriptor: CALCIUM ION, CARBONATE ION, ETHACRYNIC ACID, ... Authors: Parker, L.J. Deposit date: 2009-05-22 Release date: 2009-09-22 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
3HJM	Crystal structure of human Glutathione Transferase Pi Y108V mutant Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... Authors: Parker, L.J. Deposit date: 2009-05-22 Release date: 2009-09-22 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
3HKR	Crystal Structure of Glutathione Transferase Pi Y108V Mutant Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... Authors: Parker, L.J. Deposit date: 2009-05-25 Release date: 2009-09-22 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
1FHE	GLUTATHIONE TRANSFERASE (FH47) FROM FASCIOLA HEPATICA Descriptor: GLUTATHIONE, GLUTATHIONE TRANSFERASE Authors: Rossjohn, J, Parker, M.W. Deposit date: 1997-07-24 Release date: 1998-07-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase. J.Mol.Biol., 273, 1997
1GLQ	1.8 ANGSTROMS MOLECULAR STRUCTURE OF MOUSE LIVER CLASS PI GLUTATHIONE S-TRANSFERASE COMPLEXED WITH S-(P-NITROBENZYL)GLUTATHIONE AND OTHER INHIBITORS Descriptor: GLUTATHIONE S-TRANSFERASE YFYF, S-(P-NITROBENZYL)GLUTATHIONE Authors: Garcia-Saez, I, Coll, M. Deposit date: 1994-03-07 Release date: 1994-05-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl)glutathione and other inhibitors. J.Mol.Biol., 237, 1994
1GLP	1.8 ANGSTROMS MOLECULAR STRUCTURE OF MOUSE LIVER CLASS PI GLUTATHIONE S-TRANSFERASE COMPLEXED WITH S-(P-NITROBENZYL)GLUTATHIONE AND OTHER INHIBITORS Descriptor: GLUTATHIONE S-TRANSFERASE YFYF, GLUTATHIONE SULFONIC ACID Authors: Garcia-Saez, I, Coll, M. Deposit date: 1994-03-07 Release date: 1994-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl)glutathione and other inhibitors. J.Mol.Biol., 237, 1994
1GNE	THE THREE-DIMENSIONAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE OF SCHISTOSOMA JAPONICUM FUSED WITH A CONSERVED NEUTRALIZING EPITOPE ON GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 Descriptor: GLUTATHIONE, GLUTATHIONE S-TRANSFERASE Authors: Lim, K, Ho, J.X, Keeling, K, Gilliland, G.L, Ji, X, Ruker, F, Carter, D.C. Deposit date: 1994-06-16 Release date: 1994-11-30 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIV. Protein Sci., 3, 1994
1GUM	HUMAN GLUTATHIONE TRANSFERASE A4-4 WITHOUT LIGANDS Descriptor: PROTEIN (GLUTATHIONE TRANSFERASE A4-4) Authors: Bruns, C.M, Hubatsch, I, Ridderstrom, M, Mannervik, B, Tainer, J.A. Deposit date: 1998-06-11 Release date: 1999-01-27 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3 Å) Cite: Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products J.Mol.Biol., 288, 1999
1GTA	CRYSTAL STRUCTURES OF A SCHISTOSOMAL DRUG AND VACCINE TARGET: GLUTATHIONE S-TRANSFERASE FROM SCHISTOSOMA JAPONICA AND ITS COMPLEX WITH THE LEADING ANTISCHISTOSOMAL DRUG PRAZIQUANTEL Descriptor: GLUTATHIONE S-TRANSFERASE Authors: Mctigue, M.A, Tainer, J.A. Deposit date: 1994-12-01 Release date: 1995-02-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel. J.Mol.Biol., 246, 1995
1GSQ	THREE-DIMENSIONAL STRUCTURE, CATALYTIC PROPERTIES AND EVOLUTION OF A SIGMA CLASS GLUTATHIONE TRANSFERASE FROM SQUID, A PROGENITOR OF THE LENS-CRYSTALLINS OF CEPHALOPODS Descriptor: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE Authors: Ji, X, Rosenvinge, E.C.V, Armstrong, R.N, Gilliland, G.L. Deposit date: 1995-01-09 Release date: 1995-06-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods. Biochemistry, 34, 1995
1GUL	HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE Descriptor: GAMMA-GLUTAMYL[S-(2-IODOBENZYL)CYSTEINYL]GLYCINE, Glutathione S-transferase A4 Authors: Bruns, C.M, Hubatsch, I, Ridderstrom, M, Mannervik, B, Tainer, J.A. Deposit date: 1998-06-10 Release date: 1999-01-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products J.Mol.Biol., 288, 1999
1GTI	MODIFIED GLUTATHIONE S-TRANSFERASE (PI) COMPLEXED WITH S (P-NITROBENZYL)GLUTATHIONE Descriptor: GLUTATHIONE S-TRANSFERASE, S-(P-NITROBENZYL)GLUTATHIONE Authors: Vega, M.C, Coll, M. Deposit date: 1998-01-09 Release date: 1999-03-02 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3 Å) Cite: The three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region. J.Biol.Chem., 273, 1998
1GSY	GLUTATHIONE S-TRANSFERASE YFYF, CLASS PI, COMPLEXED WITH GLUTATHIONE Descriptor: GLUTATHIONE, GLUTATHIONE S-TRANSFERASE CLASS PI Authors: Parraga, A, Garcia-Saez, I, Coll, M. Deposit date: 1996-10-25 Release date: 1997-11-19 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.44 Å) Cite: The three-dimensional structure of a class-Pi glutathione S-transferase complexed with glutathione: the active-site hydration provides insights into the reaction mechanism. Biochem.J., 333 ( Pt 3), 1998

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