1GUL

HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE

Summary for 1GUL

DescriptorGLUTATHIONE TRANSFERASE A4-4, S-(2-iodobenzyl) glutathione (3 entities in total)
Functional Keywordsoxidative stress, alkenal degradation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O15217
Total number of polymer chains16
Total molecular weight210091.5
Authors
Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. (deposition date: 1998-06-10, release date: 1999-01-27, Last modification date: 2011-07-13)
Primary citation
Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A.
Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
J.Mol.Biol., 288:427-439, 1999
PubMed: 10329152 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1999.2697
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers200.5%4.6%0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1gul
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Molmil generated image of 1gul
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Molmil generated image of 1gul
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