3GSS

HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID-GLUTATHIONE CONJUGATE

Summary for 3GSS

DescriptorGLUTATHIONE S-TRANSFERASE P1-1, SULFATE ION, GLUTATHIONE, ... (6 entities in total)
Functional Keywordsglutathione, transferase, pi, detoxification, ethacrynic acid
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight48200.6
Authors
Oakley, A.J.,Rossjohn, J.,Parker, M.W. (deposition date: 1996-10-29, release date: 1997-11-12, Last modification date: 2011-12-14)
Primary citation
Oakley, A.J.,Rossjohn, J.,Lo Bello, M.,Caccuri, A.M.,Federici, G.,Parker, M.W.
The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate.
Biochemistry, 36:576-585, 1997
PubMed: 9012673 (PDB entries with the same primary citation)
DOI: 10.1021/bi962316i
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers50.5%5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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