3HJM

Crystal structure of human Glutathione Transferase Pi Y108V mutant

Summary for 3HJM

• Entry DOI: 10.2210/pdb3hjm/pdb
• Related: 3HJO 3HKR
• Descriptor: Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: transferase, glutathione, detoxification, mutant, polymorphism
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 94017.58

Authors

Parker, L.J. (deposition date: 2009-05-22, release date: 2009-09-22, Last modification date: 2023-11-01)

• Primary citation: Quesada-Soriano, I.,Parker, L.J.,Primavera, A.,Casas-Solvas, J.M.,Vargas-Berenguel, A.,Baron, C.,Morton, C.J.,Mazzetti, A.P.,Lo Bello, M.,Parker, M.W.,Garcia-Fuentes, L.; Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability.; Protein Sci., 18:2454-2470, 2009; PubMed: 19780048; DOI: 10.1002/pro.253

Experimental method

X-RAY DIFFRACTION (2.1 Å)