3HJM
Crystal structure of human Glutathione Transferase Pi Y108V mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutathione S-transferase P | polymer | 209 | 23182.5 | 4 | UniProt (P09211) Pfam (PF02798) Pfam (PF14497) | Homo sapiens (human) | GST class-pi, GSTP1-1 |
| 2 | E, I, Q (A, B, D) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 3 | Chemie (MES) | |||
| 3 | F, J, N, O, R (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | G, K, M, P, T (A, B, C, D) | CARBONATE ION | non-polymer | 60.0 | 5 | Chemie (CO3) | |||
| 5 | H, L, U (A, B, D) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | S (D) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 621 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 209 (UniProt: P09211)
| PDB | External Database | Details |
|---|---|---|
| Val 108 | Tyr 109 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92730.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1287.5 | |
| All* | Total formula weight | 94017.6 |
