8I2G
| FSHR-Follicle stimulating hormone-compound 716340-Gs complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | 登録日 | 2023-01-14 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14, 2023
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8I2H
| Follicle stimulating hormone receptor | 分子名称: | Follicle-stimulating hormone receptor | 著者 | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | 登録日 | 2023-01-14 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14, 2023
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8C7H
| Cryo-EM Map of the latTGF-beta 28G11 Fab complex | 分子名称: | 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ... | 著者 | Ebenhoch, R, Nar, H. | 登録日 | 2023-01-16 | 公開日 | 2023-03-01 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro. Immunohorizons, 7, 2023
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7WRQ
| Structure of Human IGF1/IGFBP3/ALS Ternary Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor-binding protein 3, Insulin-like growth factor-binding protein complex acid labile subunit, ... | 著者 | Kim, H, Fu, Y, Kim, H.M. | 登録日 | 2022-01-27 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex Nat Commun, 13, 2022
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6XFQ
| Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor | 分子名称: | Platelet glycoprotein Ib alpha chain, Snaclec agglucetin subunit alpha-1, Snaclec agglucetin subunit beta-2 | 著者 | Wang, J, Gao, Y.X, Ke, J.Y, Zhu, Z.L, Niu, L.W. | 登録日 | 2020-06-16 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor To be published
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6GFF
| Structure of GARP (LRRC32) in complex with latent TGF-beta1 and MHG-8 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat-containing protein 32, MHG-8 Fab heavy chain, ... | 著者 | Merceron, R, Lienart, S, Vanderaa, C, Colau, D, Stockis, J, Van Der Woning, B, De Haard, H, Saunders, M, Coulie, P.G, Savvides, S.N, Lucas, S. | 登録日 | 2018-04-30 | 公開日 | 2018-11-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis of latent TGF-beta 1 presentation and activation by GARP on human regulatory T cells. Science, 362, 2018
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6BXE
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5MX1
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5MX0
| Crystal structure of human fibromodulin | 分子名称: | CHLORIDE ION, Fibromodulin, NICKEL (II) ION, ... | 著者 | Paracuellos, P, Hohenester, E. | 登録日 | 2017-01-20 | 公開日 | 2017-03-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. Matrix Biol., 63, 2017
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5LFN
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4UFS
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4UFR
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4QXE
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4QXF
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4LXR
| Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Stelter, M, Parthier, C, Breithaupt, C, Stubbs, M.T. | 登録日 | 2013-07-30 | 公開日 | 2014-04-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity. Proc.Natl.Acad.Sci.USA, 111, 2014
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4LXS
| Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Stelter, M, Parthier, C, Breithaupt, C, Stubbs, M.T. | 登録日 | 2013-07-30 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity. Proc.Natl.Acad.Sci.USA, 111, 2014
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4MQW
| Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31) | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ... | 著者 | Jiang, X, Liu, H, Chen, X, He, X. | 登録日 | 2013-09-16 | 公開日 | 2014-04-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer. J.Biol.Chem., 289, 2014
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4CNC
| Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | 著者 | Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y. | 登録日 | 2014-01-21 | 公開日 | 2014-02-26 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1. Structure, 22, 2014
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4CNM
| Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | 著者 | Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y. | 登録日 | 2014-01-23 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1. Structure, 22, 2014
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4C2A
| Crystal Structure of High-Affinity von Willebrand Factor A1 domain with R1306Q and I1309V Mutations in Complex with High Affinity GPIb alpha | 分子名称: | ACETATE ION, CACODYLATE ION, CALCIUM ION, ... | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | 登録日 | 2013-08-16 | 公開日 | 2014-01-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.081 Å) | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib J.Biol.Chem., 289, 2014
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4C2B
| Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | 登録日 | 2013-08-16 | 公開日 | 2014-01-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib J.Biol.Chem., 289, 2014
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4BSU
| Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ... | 著者 | Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P. | 登録日 | 2013-06-11 | 公開日 | 2013-06-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Cell Rep., 3, 2013
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4K79
| Recognition of the Thomsen-Friedenreich Antigen by a Lamprey Variable Lymphocyte Receptor | 分子名称: | Variable lymphocyte receptor, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | 著者 | Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A. | 登録日 | 2013-04-16 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor. J.Biol.Chem., 288, 2013
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4K5U
| Recognition of the BG-H Antigen by a Lamprey Variable Lymphocyte Receptor | 分子名称: | Variable lymphocyte receptor, beta-D-galactopyranose | 著者 | Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A. | 登録日 | 2013-04-15 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor. J.Biol.Chem., 288, 2013
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4BST
| Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P6122 crystal form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1, ... | 著者 | Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P. | 登録日 | 2013-06-11 | 公開日 | 2013-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Cell Rep., 3, 2013
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