4UFS

Low resolution structure R-spondin-2 (Fu1Fu2) in complex with the ectodomains of LGR5 and ZNRF3

Summary for 4UFS

Entry DOI	10.2210/pdb4ufs/pdb
Related	4UFR
Descriptor	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-2, E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 (3 entities in total)
Functional Keywords	signaling protein, wnt, lgr, rspo
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cell membrane; Multi-pass membrane protein: O75473 Secreted : Q8BFU0 Cell membrane ; Single-pass type I membrane protein : Q5SSZ7
Total number of polymer chains	3
Total formula weight	86258.88
Authors	Zebisch, M.,Jones, E.Y. (deposition date: 2015-03-18, release date: 2015-07-08, Last modification date: 2015-08-12)
Primary citation	Zebisch, M.,Yvonne Jones, E. Crystal Structure of R-Spondin 2 in Complex with the Ectodomains of its Receptors Lgr5 and Znrf3. J.Struct.Biol., 191:149-, 2015 Cited by PubMed: 26123262 DOI: 10.1016/J.JSB.2015.05.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.8 Å)

Structure validation