4BB7
 
 | | Crystal structure of the yeast Rsc2 BAH domain | | Descriptor: | CHLORIDE ION, CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC2, GLYCEROL, ... | | Authors: | Chambers, A.L, Pearl, L.H, Oliver, A.W, Downs, J.A. | | Deposit date: | 2012-09-20 | | Release date: | 2013-08-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Bah Domain of Rsc2 is a Histone H3 Binding Domain.
Nucleic Acids Res., 41, 2013
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4YOC
 | | Crystal Structure of human DNMT1 and USP7/HAUSP complex | | Descriptor: | DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION | | Authors: | Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. | | Deposit date: | 2015-03-11 | | Release date: | 2015-05-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.916 Å) | | Cite: | Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6, 2015
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4WXX
 | | The crystal structure of human DNMT1(351-1600) | | Descriptor: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Zhang, Z.M, Song, J. | | Deposit date: | 2014-11-14 | | Release date: | 2015-07-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.622 Å) | | Cite: | Crystal Structure of Human DNA Methyltransferase 1.
J.Mol.Biol., 427, 2015
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5HH7
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5V8F
 | | Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 | | Descriptor: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (39-MER), ... | | Authors: | Yuan, Z, Riera, A, Bai, L, Sun, J, Spanos, C, Chen, Z.A, Barbon, M, Rappsilber, J, Stillman, B, Speck, C, Li, H. | | Deposit date: | 2017-03-21 | | Release date: | 2017-05-10 | | Last modified: | 2020-04-22 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Nat. Struct. Mol. Biol., 24, 2017
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5WY1
 | | Crystal structure of mouse DNA methyltransferase 1 (T1505A mutant) | | Descriptor: | DNA (cytosine-5)-methyltransferase 1, ZINC ION | | Authors: | Kanada, K, Takeshita, K, Suetake, I, Tajima, S, Nakagawa, A. | | Deposit date: | 2017-01-10 | | Release date: | 2017-05-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.27 Å) | | Cite: | Conserved threonine 1505 in the catalytic domain stabilizes mouse DNA methyltransferase 1
J. Biochem., 162, 2017
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5GUV
 | | The crystal structure of mouse DNMT1 (731-1602) mutant - R1279D | | Descriptor: | DNA (cytosine-5)-methyltransferase 1, ZINC ION | | Authors: | Ye, F, Chen, S.J. | | Deposit date: | 2016-08-31 | | Release date: | 2017-08-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.078 Å) | | Cite: | Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1.
ACS Chem. Biol., 13, 2018
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5GUT
 | | The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A | | Descriptor: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | Authors: | Chen, S.J, Ye, F. | | Deposit date: | 2016-08-31 | | Release date: | 2017-09-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1.
ACS Chem. Biol., 13, 2018
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5ZR1
 | | Saccharomyces Cerevisiae Origin Recognition Complex Bound to a 72-bp Origin DNA containing ACS and B1 element | | Descriptor: | 72bp-oring DNA, ACS305, A-rich, ... | | Authors: | Li, N, Lam, W.H, Zhai, Y, Cheng, J, Cheng, E, Zhao, Y, Gao, N, Tye, B.K. | | Deposit date: | 2018-04-21 | | Release date: | 2018-07-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of the origin recognition complex bound to DNA replication origin.
Nature, 559, 2018
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5ZNP
 | | Crystal structure of PtSHL in complex with an H3K4me3 peptide | | Descriptor: | 15-mer peptide from Histone H3.2, SHORT LIFE family protein, ZINC ION | | Authors: | Lv, X, Du, J. | | Deposit date: | 2018-04-10 | | Release date: | 2018-07-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL.
Nat Commun, 9, 2018
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5ZNR
 | | Crystal structure of PtSHL in complex with an H3K27me3 peptide | | Descriptor: | 17-mer peptide from Histone H3.2, SHORT LIFE family protein, SULFATE ION, ... | | Authors: | Lv, X, Du, J. | | Deposit date: | 2018-04-10 | | Release date: | 2018-07-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.202 Å) | | Cite: | Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL.
Nat Commun, 9, 2018
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5Z8N
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5Z8L
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6OM3
 | | Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle | | Descriptor: | DNA (146-MER), DNA (147-MER), Histone H2A, ... | | Authors: | De Ioannes, P.E, Wang, M, Armache, K.-J. | | Deposit date: | 2019-04-18 | | Release date: | 2019-07-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure and function of the Orc1 BAH-nucleosome complex.
Nat Commun, 10, 2019
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6K15
 | | RSC substrate-recruitment module | | Descriptor: | Chromatin structure-remodeling complex protein RSC3, Chromatin structure-remodeling complex protein RSC30, Chromatin structure-remodeling complex protein RSC58, ... | | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | Deposit date: | 2019-05-09 | | Release date: | 2019-11-13 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
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6KW3
 | | The ClassA RSC-Nucleosome Complex | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | Deposit date: | 2019-09-05 | | Release date: | 2019-11-13 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (7.13 Å) | | Cite: | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
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6KW4
 | | The ClassB RSC-Nucleosome Complex | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | Deposit date: | 2019-09-06 | | Release date: | 2019-11-13 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (7.55 Å) | | Cite: | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
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6RQC
 | | Cryo-EM structure of an MCM loading intermediate | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (88-MER), ... | | Authors: | Miller, T.C.R, Locke, J, Costa, A. | | Deposit date: | 2019-05-15 | | Release date: | 2019-11-20 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.
Nature, 575, 2019
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6V8O
 | | RSC core | | Descriptor: | Chromatin structure-remodeling complex protein RSC14, Chromatin structure-remodeling complex protein RSC3, Chromatin structure-remodeling complex protein RSC30, ... | | Authors: | Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E. | | Deposit date: | 2019-12-11 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.
Elife, 8, 2019
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6V92
 | | RSC-NCP | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC14, ... | | Authors: | Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E. | | Deposit date: | 2019-12-13 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.
Elife, 8, 2019
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6OXB
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6W8V
 | | Crystal structure of mouse DNMT1 in complex with ACG DNA | | Descriptor: | ACG DNA (5'-D(*AP*CP*TP*TP*AP*(C49)P*GP*GP*AP*AP*GP*G)-3'), ACG DNA (5'-D(*CP*CP*TP*TP*CP*(5CM)P*GP*TP*AP*AP*GP*T)-3'), DNA (cytosine-5)-methyltransferase 1, ... | | Authors: | Anteneh, H, Song, J. | | Deposit date: | 2020-03-21 | | Release date: | 2020-07-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.12 Å) | | Cite: | DNMT1 activity, base flipping mechanism and genome-wide DNA methylation are regulated by the DNA sequence context
Nat Commun, 2020
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6W8W
 | | Crystal structure of mouse DNMT1 in complex with CCG DNA | | Descriptor: | CCG DNA (5'-D(*AP*CP*TP*TP*AP*(5CM)P*GP*GP*AP*AP*GP*G)-3'), CCG DNA (5'-D(*CP*CP*TP*TP*CP*(C49)P*GP*TP*AP*AP*GP*T)-3'), DNA (cytosine-5)-methyltransferase 1, ... | | Authors: | Anteneh, H, Song, J. | | Deposit date: | 2020-03-21 | | Release date: | 2020-07-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | DNMT1 activity, base flipping mechanism and genome-wide DNA methylation are regulated by the DNA sequence context
Nat Commun, 2020
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6WGI
 | | Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution | | Descriptor: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ... | | Authors: | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | | Deposit date: | 2020-04-05 | | Release date: | 2020-07-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (10 Å) | | Cite: | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6WGG
 | | Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | | Descriptor: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ... | | Authors: | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | | Deposit date: | 2020-04-05 | | Release date: | 2020-07-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (8.1 Å) | | Cite: | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
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