5GUV
The crystal structure of mouse DNMT1 (731-1602) mutant - R1279D
Summary for 5GUV
| Entry DOI | 10.2210/pdb5guv/pdb |
| Related | 5GUT |
| Descriptor | DNA (cytosine-5)-methyltransferase 1, ZINC ION (3 entities in total) |
| Functional Keywords | mutant, transferase |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 98982.18 |
| Authors | Ye, F.,Chen, S.J. (deposition date: 2016-08-31, release date: 2017-08-30, Last modification date: 2023-11-08) |
| Primary citation | Ye, F.,Kong, X.Q.,Zhang, H.,Liu, Y.,Shao, Z.,Jin, J.,Cai, Y.,Zhang, R.,Li, L.,Zhang, Y.W.,Liu, Y.C.,Zhang, C.,Xie, W.,Yu, K.,Ding, H.,Zhao, K.,Chen, S.,Jiang, H.,Baylin, S.B.,Luo, C. Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13:772-781, 2018 Cited by PubMed: 29381856DOI: 10.1021/acschembio.7b00890 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.078 Å) |
Structure validation
Download full validation report
