6RQC

Cryo-EM structure of an MCM loading intermediate

This is a non-PDB format compatible entry.

Summary for 6RQC

• Entry DOI: 10.2210/pdb6rqc/pdb
• EMDB information: 4980
• Descriptor: Origin recognition complex subunit 1, Minichromosome maintenance protein 5, DNA replication licensing factor MCM6, ... (18 entities in total)
• Functional Keywords: dna replication, origin licensing, mcm2-7 helicase, origin recognition complex, replication
• Biological source: Saccharomyces cerevisiae S288c (Baker's yeast); More
• Total number of polymer chains: 14
• Total formula weight: 1086942.90

Authors

Miller, T.C.R.,Locke, J.,Costa, A. (deposition date: 2019-05-15, release date: 2019-11-20, Last modification date: 2019-12-11)

• Primary citation: Miller, T.C.R.,Locke, J.,Greiwe, J.F.,Diffley, J.F.X.,Costa, A.; Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.; Nature, 575:704-710, 2019; PubMed: 31748745; DOI: 10.1038/s41586-019-1768-0

Experimental method

ELECTRON MICROSCOPY (4.4 Å)