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5U0C
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Structure of Zika virus NS5 RNA polymerase domain
分子名称: NS5 RNA polymerase domain, ZINC ION
著者Zhao, B, Du, F.
登録日2016-11-23
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and function of the Zika virus full-length NS5 protein.
Nat Commun, 8, 2017
5U0B
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Structure of full-length Zika virus NS5
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Zhao, B, Du, F.
登録日2016-11-23
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and function of the Zika virus full-length NS5 protein.
Nat Commun, 8, 2017
5IQ6
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Crystal structure of Dengue virus serotype 3 RNA dependent RNA polymerase bound to HeE1-2Tyr, a new pyridobenzothizole inhibitor
分子名称: N-[8-(cyclohexyloxy)-1-oxo-2-phenyl-1H-pyrido[2,1-b][1,3]benzothiazole-4-carbonyl]-L-tyrosine, RNA dependent RNA polymerase, ZINC ION
著者Tarantino, D, Mastrangelo, E, Milani, M.
登録日2016-03-10
公開日2016-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor.
Antiviral Res., 134, 2016
2HFZ
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BU of 2hfz by Molmil
Crystal structure of RNA dependent RNA polymerase domain from West Nile virus
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase(NS5), ZINC ION
著者Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP)
登録日2006-06-26
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
6QSN
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Crystal structure of Yellow fever virus polymerase NS5A
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Boura, E, Dubankova, A.
登録日2019-02-21
公開日2019-10-16
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses.
Antiviral Res., 169, 2019
6UX2
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Crystal structure of ZIKV RdRp in complex with STAT2
分子名称: Nonstructural Protein 5, SULFATE ION, Signal transducer and activator of transcription 2, ...
著者Wang, B, Song, J.
登録日2019-11-06
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural basis for STAT2 suppression by flavivirus NS5.
Nat.Struct.Mol.Biol., 27, 2020
5TFR
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BU of 5tfr by Molmil
Crystal structure of Zika Virus NS5 protein
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Longenecker, K.L, Upadhyay, A.K.
登録日2016-09-26
公開日2016-10-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6KR2
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BU of 6kr2 by Molmil
Crystal structure of Dengue virus nonstructural protein NS5 (form 1)
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Wu, J, Lu, G, Ye, H.Q, Gong, P.
登録日2019-08-20
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase.
Plos Pathog., 16, 2020
7D6N
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BU of 7d6n by Molmil
Crystal structure of tick-borne encephalitis virus RNA-dependent RNA polymerase
分子名称: MAGNESIUM ION, Tick-borne encephalitis virus RNA-dependent RNA polymerase, ZINC ION
著者Yang, J, Jing, X, Gong, P.
登録日2020-10-01
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.168 Å)
主引用文献Crystal structure of tick-borne encephalitis virus
Nucleic Acids Res., 2020
8WU3
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BU of 8wu3 by Molmil
Crystal structure of RNA-dependent RNA polymerases from Alongshan virus
分子名称: RNA polymerase
著者Liu, Z.Y, Han, P, Peng, Q, Qi, J.X.
登録日2023-10-20
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of RNA-dependent RNA polymerases from Jingmen tick virus and Alongshan virus
HLIFE, 2, 2024
8CXG
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BU of 8cxg by Molmil
Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy
分子名称: Ankyrin repeat family A protein 2,Envelope E protein, C8 scFv heavy chain, C8 scFv light chain, ...
著者Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H.
登録日2022-05-21
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy
To Be Published
8CXH
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Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy
分子名称: Ankyrin repeat family A protein 2,Envelope E protein, C10 heavy chain, C10 light chain, ...
著者Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H.
登録日2022-05-21
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy
To Be Published
5TMH
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BU of 5tmh by Molmil
Structure of Zika virus NS5
分子名称: GLYCEROL, Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Wang, B, Tan, X, Song, J.
登録日2016-10-12
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.278 Å)
主引用文献The structure of Zika virus NS5 reveals a conserved domain conformation.
Nat Commun, 8, 2017
8T12
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Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 ordered.
分子名称: Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION
著者Biswal, M, Lu, J, Song, J.
登録日2023-06-01
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 ordered.
To Be Published
8CXI
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BU of 8cxi by Molmil
Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy
分子名称: A11 heavy chain, A11 light chain, Ankyrin repeat family A protein 2,Envelope E protein, ...
著者Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H.
登録日2022-05-21
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy
To Be Published
8T13
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BU of 8t13 by Molmil
Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 disordered
分子名称: Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION
著者Biswal, M, Lu, J, Song, J.
登録日2023-06-01
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 disordered
To Be Published
8GZP
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BU of 8gzp by Molmil
Cryo-EM structure of the NS5-SLA complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ...
著者Osawa, T, Ehara, H, Sekine, S.
登録日2022-09-27
公開日2023-08-02
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of dengue virus RNA replicase complexes.
Mol.Cell, 83, 2023
5CCV
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BU of 5ccv by Molmil
Crystal structure of full-length NS5 from dengue virus type 3
分子名称: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Klema, V.J, Choi, K.H.
登録日2015-07-02
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface.
Plos Pathog., 12, 2016
4MTP
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BU of 4mtp by Molmil
RdRp from Japanesese Encephalitis Virus
分子名称: RNA dependent RNA polymerase, ZINC ION
著者Surana, P, Nair, D.T.
登録日2013-09-20
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state.
Nucleic Acids Res., 42, 2014
8GZQ
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BU of 8gzq by Molmil
Cryo-EM structure of the NS5-NS3-SLA complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, Genome polyprotein, RNA, ...
著者Osawa, T, Ehara, H, Sekine, S.
登録日2022-09-27
公開日2023-08-02
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of dengue virus RNA replicase complexes.
Mol.Cell, 83, 2023
6I7P
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BU of 6i7p by Molmil
Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
分子名称: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N.
登録日2018-11-16
公開日2019-04-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.975 Å)
主引用文献Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
6WCZ
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BU of 6wcz by Molmil
CryoEM structure of full-length ZIKV NS5-hSTAT2 complex
分子名称: Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION
著者Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S.
登録日2020-03-31
公開日2020-07-08
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for STAT2 suppression by flavivirus NS5.
Nat.Struct.Mol.Biol., 27, 2020
5M2Z
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BU of 5m2z by Molmil
Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
分子名称: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N.
登録日2016-10-13
公開日2018-06-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.8 Å)
主引用文献Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
5M2X
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BU of 5m2x by Molmil
Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
分子名称: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N.
登録日2016-10-13
公開日2018-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4.991 Å)
主引用文献Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
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