4OUN
 
 | | Crystal Structure of Mini-ribonuclease 3 from Bacillus subtilis | | Descriptor: | Mini-ribonuclease 3 | | Authors: | Chojnowski, G, Czarnecka, J, Nowak, E, Pianka, D, Glow, D, Sabala, I, Skowronek, K, Nowotny, M, Bujnicki, J.M. | | Deposit date: | 2014-02-18 | | Release date: | 2015-02-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Sequence-specific cleavage of dsRNA by Mini-III RNase
Nucleic Acids Res., 43, 2015
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2GSL
 | | X-Ray Crystal Structure of Protein FN1578 from Fusobacterium nucleatum. Northeast Structural Genomics Consortium Target NR1. | | Descriptor: | Hypothetical protein, MAGNESIUM ION | | Authors: | Forouhar, F, Su, M, Jayaraman, S, Conover, K, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-04-26 | | Release date: | 2006-05-09 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of the Hypothetical Protein (FN1578) from Fusobacterium nucleatum, NESG Target NR1
To be Published
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1I4S
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1JFZ
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2EB1
 | | Crystal Structure of the C-Terminal RNase III Domain of Human Dicer | | Descriptor: | Endoribonuclease Dicer, MAGNESIUM ION | | Authors: | Takeshita, D, Zenno, S, Lee, W.C, Nagata, K, Saigo, K, Tanokura, M. | | Deposit date: | 2007-02-05 | | Release date: | 2007-11-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Homodimeric Structure and Double-stranded RNA Cleavage Activity of the C-terminal RNase III Domain of Human Dicer
J.Mol.Biol., 374, 2007
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1RC5
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1U61
 | | Crystal Structure of Putative Ribonuclease III from Bacillus cereus | | Descriptor: | hypothetical protein | | Authors: | Osipiuk, J, Quartey, P, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2004-07-29 | | Release date: | 2004-09-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | X-ray crystal structure of conserved hypothetical protein from Bacillus cereus
To be Published
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2QVW
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2FFL
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3C4B
 | | Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | | Descriptor: | Endoribonuclease Dicer | | Authors: | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | | Deposit date: | 2008-01-29 | | Release date: | 2008-02-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C4T
 | | Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | | Descriptor: | CADMIUM ION, Endoribonuclease Dicer | | Authors: | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | | Deposit date: | 2008-01-30 | | Release date: | 2008-02-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3RV1
 | | Crystal structure of the N-terminal and RNase III domains of K. polysporus Dcr1 E224Q mutant | | Descriptor: | K. polysporus Dcr1 | | Authors: | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | | Deposit date: | 2011-05-05 | | Release date: | 2011-08-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.975 Å) | | Cite: | The inside-out mechanism of dicers from budding yeasts.
Cell(Cambridge,Mass.), 146, 2011
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4OOG
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3J6B
 | | Structure of the yeast mitochondrial large ribosomal subunit | | Descriptor: | 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ... | | Authors: | Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. | | Deposit date: | 2014-01-22 | | Release date: | 2014-04-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
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5T16
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5ZAM
 | | Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | | Descriptor: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) | | Authors: | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | | Deposit date: | 2018-02-07 | | Release date: | 2018-05-09 | | Last modified: | 2020-08-05 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
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5B16
 | | X-ray structure of DROSHA in complex with the C-terminal tail of DGCR8. | | Descriptor: | Microprocessor complex subunit DGCR8, Ribonuclease 3,DROSHA,Ribonuclease 3,DROSHA,Ribonuclease 3, ZINC ION | | Authors: | Kwon, S.C, Nguyen, T.A, Choi, Y.G, Jo, M.H, Hohng, S, Kim, V.N, Woo, J.S. | | Deposit date: | 2015-11-23 | | Release date: | 2016-02-03 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of Human DROSHA
Cell, 164, 2016
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8HF0
 | | DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state | | Descriptor: | Dicer-2, isoform A, LD06392p, ... | | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | | Deposit date: | 2022-11-09 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.72 Å) | | Cite: | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
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8HF1
 | | DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state | | Descriptor: | Dicer-2, isoform A, LD06392p, ... | | Authors: | Su, S, Wang, J, Ma, J. | | Deposit date: | 2022-11-09 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
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4M2Z
 | | Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE) | | Descriptor: | CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA10, ... | | Authors: | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | | Deposit date: | 2013-08-05 | | Release date: | 2013-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | RNase III: Genetics and Function; Structure and Mechanism.
Annu. Rev. Genet., 47, 2013
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4M30
 | | Crystal structure of RNASE III complexed with double-stranded RNA AND AMP (TYPE II CLEAVAGE) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | | Deposit date: | 2013-08-05 | | Release date: | 2013-12-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | RNase III: Genetics and Function; Structure and Mechanism.
Annu. Rev. Genet., 47, 2013
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3RV0
 | | Crystal structure of K. polysporus Dcr1 without the C-terminal dsRBD | | Descriptor: | K. polysporus Dcr1, MAGNESIUM ION | | Authors: | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | | Deposit date: | 2011-05-05 | | Release date: | 2011-08-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | The inside-out mechanism of dicers from budding yeasts.
Cell(Cambridge,Mass.), 146, 2011
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6LXD
 | | Pri-miRNA bound DROSHA-DGCR8 complex | | Descriptor: | Microprocessor complex subunit DGCR8, RNA (102-mer), Ribonuclease 3, ... | | Authors: | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | | Deposit date: | 2020-02-10 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
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6LXE
 | | DROSHA-DGCR8 complex | | Descriptor: | Microprocessor complex subunit DGCR8, Ribonuclease 3, ZINC ION | | Authors: | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | | Deposit date: | 2020-02-10 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
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2EZ6
 | | Crystal structure of Aquifex aeolicus RNase III (D44N) complexed with product of double-stranded RNA processing | | Descriptor: | 28-MER, MAGNESIUM ION, Ribonuclease III | | Authors: | Gan, J, Tropea, J.E, Austin, B.P, Court, D.L, Waugh, D.S, Ji, X. | | Deposit date: | 2005-11-10 | | Release date: | 2006-02-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Insight into the Mechanism of Double-Stranded RNA Processing by Ribonuclease III.
Cell(Cambridge,Mass.), 124, 2006
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