3T6P
| IAP antagonist-induced conformational change in cIAP1 promotes E3 ligase activation via dimerization | 分子名称: | Baculoviral IAP repeat-containing protein 2, ZINC ION | 著者 | Dueber, E.C, Schoeffler, A.J, Lingel, A, Elliott, M, Fedorova, A.V, Giannetti, A.M, Zobel, K, Maurer, B, Varfolomeev, E, Wu, P, Wallweber, H, Hymowitz, S, Deshayes, K, Vucic, D, Fairbrother, W.J. | 登録日 | 2011-07-28 | 公開日 | 2011-11-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. Science, 334, 2011
|
|
3YGS
| APAF-1 CARD IN COMPLEX WITH PRODOMAIN OF PROCASPASE-9 | 分子名称: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1, PROCASPASE 9 | 著者 | Qin, H, Srinivasula, S, Wu, G, Fernandes-Alnemri, T, Alnemri, E, Shi, Y. | 登録日 | 1999-05-08 | 公開日 | 2000-04-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature, 399, 1999
|
|
4E9M
| |
4I16
| Crystal structure of CARMA1 CARD | 分子名称: | Caspase recruitment domain-containing protein 11, SULFATE ION | 著者 | Li, S, Yang, X, Shen, Y. | 登録日 | 2012-11-20 | 公開日 | 2012-12-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | 主引用文献 | Structural insights into the assembly of CARMA1 and BCL10 Plos One, 7, 2012
|
|
4IFP
| X-ray Crystal Structure of Human NLRP1 CARD Domain | 分子名称: | MALONATE ION, Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 1, ... | 著者 | Jin, T, Curry, J, Smith, P, Jiang, J, Xiao, T. | 登録日 | 2012-12-14 | 公開日 | 2013-04-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9948 Å) | 主引用文献 | Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1. Proteins, 81, 2013
|
|
4IKM
| X-ray structure of CARD8 CARD domain | 分子名称: | 1,2-ETHANEDIOL, IODIDE ION, Maltose-binding periplasmic protein, ... | 著者 | Jin, T, Huang, M, Smith, P, Jiang, J, Xiao, T. | 登録日 | 2012-12-26 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4606 Å) | 主引用文献 | The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces. Acta Crystallogr.,Sect.F, 69, 2013
|
|
4IRL
| X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Jin, T, Huang, M, Smith, P, Xiao, T. | 登録日 | 2013-01-15 | 公開日 | 2013-08-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein. Acta Crystallogr.,Sect.F, 69, 2013
|
|
4JQW
| Crystal Structure of a Complex of NOD1 CARD and Ubiquitin | 分子名称: | Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C | 著者 | Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S. | 登録日 | 2013-03-20 | 公開日 | 2014-03-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of a complex of NOD1 CARD and ubiquitin Plos One, 9, 2014
|
|
4JUP
| Dimeric structure of CARMA1 CARD | 分子名称: | Caspase recruitment domain-containing protein 11 | 著者 | Park, H.H. | 登録日 | 2013-03-25 | 公開日 | 2014-02-05 | 最終更新日 | 2018-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Novel Disulfide Bond-Mediated Dimerization of the CARD Domain Was Revealed by the Crystal Structure of CARMA1 CARD Plos One, 8, 2013
|
|
4KXF
| |
4LWD
| Human CARMA1 CARD domain | 分子名称: | Caspase recruitment domain-containing protein 11, MAGNESIUM ION, SULFATE ION | 著者 | Zheng, C, Wu, H. | 登録日 | 2013-07-26 | 公開日 | 2013-10-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly. Mol.Cell, 51, 2013
|
|
4M9S
| crystal structure of CED-4 bound CED-3 fragment | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | 登録日 | 2013-08-15 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev., 27, 2013
|
|
4M9X
| Crystal structure of CED-4 bound CED-3 fragment | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | 登録日 | 2013-08-15 | 公開日 | 2013-10-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.344 Å) | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev., 27, 2013
|
|
4M9Y
| Crystal structure of CED-4 bound CED-3 fragment | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | 登録日 | 2013-08-15 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev., 27, 2013
|
|
4M9Z
| Crystal structure of CED-4 bound CED-3 fragment | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | 登録日 | 2013-08-15 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.405 Å) | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev., 27, 2013
|
|
4RHW
| Crystal structure of Apaf-1 CARD and caspase-9 CARD complex | 分子名称: | Apoptotic protease-activating factor 1, CHLORIDE ION, Caspase-9, ... | 著者 | Hu, Q, Wu, D, Yan, C, Shi, Y. | 登録日 | 2014-10-03 | 公開日 | 2014-10-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome. Proc. Natl. Acad. Sci. U.S.A., 111, 2014
|
|
4UZ0
| Crystal Structure of apoptosis repressor with CARD (ARC) | 分子名称: | GLYCEROL, NUCLEOLAR PROTEIN 3 | 著者 | Kim, S.H, Jeong, J.H, Jang, T.H, Kim, Y.G, Park, H.H. | 登録日 | 2014-09-04 | 公開日 | 2015-07-01 | 最終更新日 | 2017-07-12 | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | 主引用文献 | Crystal Structure of Caspase Recruiting Domain (Card) of Apoptosis Repressor with Card (Arc) and its Implication in Inhibition of Apoptosis. Sci.Rep., 5, 2015
|
|
5AJ2
| Cryo electron tomography of the Naip5-Nlrc4 inflammasome | 分子名称: | NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 | 著者 | Diebolder, C.A, Halff, E.F, Koster, A.J, Huizinga, E.G, Koning, R.I. | 登録日 | 2015-02-20 | 公開日 | 2015-11-11 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (40 Å) | 主引用文献 | Cryoelectron Tomography of the Naip5/Nlrc4 Inflammasome: Implications for Nlr Activation. Structure, 23, 2015
|
|
5FNA
| Cryo-EM reconstruction of caspase-1 CARD | 分子名称: | Caspase-1 | 著者 | Li, Y, Lu, A, Schmidt, F.I, Yin, Q, Chen, S, Fu, T.M, Tong, A.B, Ploegh, H.L, Mao, Y, Wu, H. | 登録日 | 2015-11-11 | 公開日 | 2016-03-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism Nat.Struct.Mol.Biol., 23, 2016
|
|
5GPQ
| Crystal Structure of zebrafish ASC CARD Domain | 分子名称: | CITRIC ACID, Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Jin, T, Li, Y. | 登録日 | 2016-08-04 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional and structural characterization of zebrafish ASC. FEBS J., 285, 2018
|
|
5H8O
| Crystal structure of an ASC-binding nanobody in complex with the CARD domain of ASC | 分子名称: | Apoptosis-associated speck-like protein containing a CARD, VHH nanobody | 著者 | Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L. | 登録日 | 2015-12-23 | 公開日 | 2016-04-06 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (4.206 Å) | 主引用文献 | A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. J.Exp.Med., 213, 2016
|
|
5JUY
| Active human apoptosome with procaspase-9 | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Caspase-9, ... | 著者 | Cheng, T.C, Hong, C, Akey, I.V, Yuan, S, Akey, C.W. | 登録日 | 2016-05-10 | 公開日 | 2016-10-19 | 最終更新日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | A near atomic structure of the active human apoptosome. Elife, 5, 2016
|
|
5WVC
| Structure of the CARD-CARD disk | 分子名称: | Apoptotic protease-activating factor 1, Caspase, IODIDE ION | 著者 | Lin, S.C, Lo, Y.C, Su, T.W. | 登録日 | 2016-12-24 | 公開日 | 2017-04-19 | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | 主引用文献 | Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome. Structure, 25, 2017
|
|
5WVE
| Apaf-1-Caspase-9 holoenzyme | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Caspase, ... | 著者 | Li, Y, Zhou, M, Hu, Q, Shi, Y. | 登録日 | 2016-12-24 | 公開日 | 2017-02-08 | 最終更新日 | 2017-03-01 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5YRN
| Structure of RIP2 CARD domain | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | 著者 | Wu, B, Gong, Q. | 登録日 | 2017-11-09 | 公開日 | 2018-11-14 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of RIP2 activation and signaling. Nat Commun, 9, 2018
|
|