9BDX
 
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1PZU
 | | An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site | | Descriptor: | 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', 5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... | | Authors: | Jin, L, Sliz, P, Chen, L, Macian, F, Rao, A, Hogan, P.G, Harrison, S.C. | | Deposit date: | 2003-07-14 | | Release date: | 2003-09-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site
Nat.Struct.Biol., 10, 2003
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1RAM
 | | A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA (5'-D(*CP*GP*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR NF-KB P65) | | Authors: | Chen, Y.-Q, Ghosh, S, Ghosh, G. | | Deposit date: | 1997-11-22 | | Release date: | 1998-05-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A novel DNA recognition mode by the NF-kappa B p65 homodimer.
Nat.Struct.Biol., 5, 1998
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8TKM
 | | Murine NF-kappaB p50 Rel Homology Region homodimer in complex with 17-mer kappaB DNA from human interleukin-6 (IL-6) promoter | | Descriptor: | 17-mer kappaB DNA, Nuclear factor NF-kappa-B p50 subunit | | Authors: | Zhu, N, Mealka, M, Mitchel, S, Rogers, W.E, Huxford, T. | | Deposit date: | 2023-07-25 | | Release date: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray Crystallographic Study of Preferred Spacing by the NF-kappa B p50 Homodimer on kappa B DNA.
Biomolecules, 13, 2023
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8TKN
 | | Murine NF-kappaB p50 Rel Homology Region homodimer in complex with 10-mer kappaB DNA from human Neutrophil Gelatinase-associated Lipocalin (NGAL) promoter | | Descriptor: | DNA A, DNA B, Nuclear factor NF-kappa-B p50 subunit | | Authors: | Zhu, N, Mealka, M, Mitchel, S, Rogers, W.E, Huxford, T. | | Deposit date: | 2023-07-25 | | Release date: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray Crystallographic Study of Preferred Spacing by the NF-kappa B p50 Homodimer on kappa B DNA.
Biomolecules, 13, 2023
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8TKL
 | | Murine NF-kappaB p50 Rel Homology Region homodimer in complex with a Test 16-mer kappaB-like DNA | | Descriptor: | Nuclear factor NF-kappa-B p50 subunit, Test 17-mer kappaB-like DNA | | Authors: | Mitchel, S, Mealka, M, Rogers, W.E, Milani, C, Acuna, L.M, Huxford, T. | | Deposit date: | 2023-07-25 | | Release date: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray Crystallographic Study of Preferred Spacing by the NF-kappa B p50 Homodimer on kappa B DNA.
Biomolecules, 13, 2023
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1SVC
 | | NFKB P50 HOMODIMER BOUND TO DNA | | Descriptor: | DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB)) | | Authors: | Mueller, C.W, Harrison, S.C. | | Deposit date: | 1995-11-27 | | Release date: | 1996-06-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the NF-kappa B p50 homodimer bound to DNA.
Nature, 373, 1995
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1LE5
 | | Crystal structure of a NF-kB heterodimer bound to an IFNb-kB | | Descriptor: | 5'-D(*AP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*T)-3', Nuclear factor NF-kappa-B p50 subunit, ... | | Authors: | Berkowitz, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G. | | Deposit date: | 2002-04-09 | | Release date: | 2003-04-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The X-ray crystal structure of the
NF-kB p50/p65 heterodimer bound
to the Interferon beta-kB site
J.Biol.Chem., 277, 2002
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1LEI
 | | The kB DNA sequence from the HLV-LTR functions as an allosteric regulator of HIV transcription | | Descriptor: | 5'-D(*CP*TP*CP*AP*GP*GP*GP*AP*AP*AP*GP*TP*AP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*5ITP*AP*CP*5ITP*5ITP*5ITP*CP*CP*CP*TP*GP*AP*G)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ... | | Authors: | Chen-Park, F, Huang, D.B, Ghosh, G. | | Deposit date: | 2002-04-09 | | Release date: | 2003-04-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The kB DNA sequence from the HIV Long Terminal Repeat functions as an allosteric regulator of HIV transcription
J.Biol.Chem., 277, 2002
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1LE9
 | | Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti | | Descriptor: | 5'-D(*AP*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*T)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ... | | Authors: | Benjamin, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G. | | Deposit date: | 2002-04-09 | | Release date: | 2003-04-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site.
J.Biol.Chem., 277, 2002
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1NFK
 | | STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER | | Descriptor: | DNA (5'-D(*TP*GP*GP*GP*AP*AP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB)) | | Authors: | Ghosh, G, Van Duyne, G, Ghosh, S, Sigler, P.B. | | Deposit date: | 1995-02-28 | | Release date: | 1996-12-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of NF-kappa B p50 homodimer bound to a kappa B site.
Nature, 373, 1995
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1P7H
 | | Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element | | Descriptor: | 5'-D(*AP*AP*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*A)-3', 5'-D(*TP*TP*TP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... | | Authors: | Giffin, M.J, Stroud, J.C, Bates, D.L, von Koenig, K.D, Hardin, J, Chen, L. | | Deposit date: | 2003-05-01 | | Release date: | 2003-09-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element
Nat.Struct.Biol., 10, 2003
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1OOA
 | | CRYSTAL STRUCTURE OF NF-kB(p50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit, RNA aptamer | | Authors: | Huang, D.B, Vu, D, Cassiday, L.A, Zimmerman, J.M, Maher III, L.J, Ghosh, G. | | Deposit date: | 2003-03-03 | | Release date: | 2003-07-22 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer.
Proc.Natl.Acad.Sci.USA, 100, 2003
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1OWR
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3QRF
 | | Structure of a domain-swapped FOXP3 dimer | | Descriptor: | Forkhead box protein P3, MAGNESIUM ION, Nuclear factor of activated T-cells, ... | | Authors: | Bandukwala, H.S, Wu, Y, Feurer, M, Chen, Y, Barbosa, B, Ghosh, S, Stroud, J.C, Benoist, C, Mathis, D, Rao, A, Chen, L. | | Deposit date: | 2011-02-17 | | Release date: | 2011-04-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Immunity, 34, 2011
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5ZMC
 | | Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2 | | Descriptor: | DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3'), Nuclear factor NF-kappa-B p100 subunit, ... | | Authors: | Xu, X, Bharath, S.R, Song, H. | | Deposit date: | 2018-04-02 | | Release date: | 2018-09-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1.
Nat Commun, 9, 2018
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2AS5
 | | Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA. | | Descriptor: | 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', 5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', Forkhead box protein P2, ... | | Authors: | Wu, Y, Stroud, J.C, Borde, M, Bates, D.L, Guo, L, Han, A, Rao, A, Chen, L. | | Deposit date: | 2005-08-22 | | Release date: | 2006-08-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126, 2006
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1IKN
 | | IKAPPABALPHA/NF-KAPPAB COMPLEX | | Descriptor: | PROTEIN (I-KAPPA-B-ALPHA), PROTEIN (NF-KAPPA-B P50D SUBUNIT), PROTEIN (NF-KAPPA-B P65 SUBUNIT) | | Authors: | Huxford, T, Huang, D.-B, Malek, S, Ghosh, G. | | Deposit date: | 1998-11-13 | | Release date: | 1999-04-12 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation.
Cell(Cambridge,Mass.), 95, 1998
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1A02
 | | STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA | | Descriptor: | AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ... | | Authors: | Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C. | | Deposit date: | 1997-12-08 | | Release date: | 1998-05-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Nature, 392, 1998
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1S9K
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1NFI
 | | I-KAPPA-B-ALPHA/NF-KAPPA-B COMPLEX | | Descriptor: | I-KAPPA-B-ALPHA, NF-KAPPA-B P50, NF-KAPPA-B P65 | | Authors: | Jacobs, M.D, Harrison, S.C. | | Deposit date: | 1998-08-25 | | Release date: | 1998-11-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of an IkappaBalpha/NF-kappaB complex.
Cell(Cambridge,Mass.), 95, 1998
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