1IKN

IKAPPABALPHA/NF-KAPPAB COMPLEX

Summary for 1IKN
DescriptorPROTEIN (NF-KAPPA-B P65 SUBUNIT), PROTEIN (NF-KAPPA-B P50D SUBUNIT), PROTEIN (I-KAPPA-B-ALPHA), ... (4 entities in total)
Functional Keywordstranscription factor, ikb-nfkb complex
Biological sourceMus musculus (house mouse)
More
Cellular locationNucleus: Q04207
Nucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus: P25799
Cytoplasm: P25963
Total number of polymer chains3
Total formula weight72766.02
Authors
Huxford, T.,Huang, D.-B.,Malek, S.,Ghosh, G. (deposition date: 1998-11-13, release date: 1999-04-12, Last modification date: 2011-07-13)
Primary citationGhosh, G.,Huang, D.B.,Huxford, T.,Malek, S.
The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation.
Cell(Cambridge,Mass.), 95:759-770, 1998
PubMed: 9865694
DOI: 110.1016/S0092-8674(00)81699-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation
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PDB entries from 2021-06-16