1LE5

Crystal structure of a NF-kB heterodimer bound to an IFNb-kB

Summary for 1LE5

• Entry DOI: 10.2210/pdb1le5/pdb
• Related: 1LE9 1LEI 1VKX
• Descriptor: 5'-D(*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*T)-3', 5'-D(*AP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3', Nuclear factor NF-kappa-B p65 subunit, ... (5 entities in total)
• Functional Keywords: protein-dna complex, transcription factors, rel/nf-kb protein, transcription-dna complex, transcription/dna
• Biological source: Mus musculus (house mouse); More
• Cellular location: Nucleus: Q04207; Nucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus: P25799
• Total number of polymer chains: 8
• Total formula weight: 146990.24

Authors

Berkowitz, B.,Huang, D.B.,Chen-Park, F.E.,Sigler, P.B.,Ghosh, G. (deposition date: 2002-04-09, release date: 2003-04-15, Last modification date: 2023-09-20)

• Primary citation: Berkowitz, B.,Huang, D.B.,Chen-Park, F.E.,Sigler, P.B.,Ghosh, G.; The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the Interferon beta-kB site; J.Biol.Chem., 277:24694-24700, 2002; PubMed: 11970948; DOI: 10.1074/jbc.M200006200

Experimental method

X-RAY DIFFRACTION (2.75 Å)