1LEI
The kB DNA sequence from the HLV-LTR functions as an allosteric regulator of HIV transcription
Summary for 1LEI
Entry DOI | 10.2210/pdb1lei/pdb |
Related | 1VKX |
Descriptor | 5'-D(*CP*TP*CP*AP*GP*GP*GP*AP*AP*AP*GP*TP*AP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*5ITP*AP*CP*5ITP*5ITP*5ITP*CP*CP*CP*TP*GP*AP*G)-3', NUCLEAR FACTOR NF-KAPPA-B P65 SUBUNIT, ... (5 entities in total) |
Functional Keywords | transcription factor, nf-kb-dna complex, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (house mouse) More |
Cellular location | Nucleus: 1LEI Nucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus: 1LEI |
Total number of polymer chains | 4 |
Total formula weight | 77032.56 |
Authors | Chen-Park, F.,Huang, D.B.,Ghosh, G. (deposition date: 2002-04-09, release date: 2003-04-15, Last modification date: 2023-09-20) |
Primary citation | Chen-Park, F.E.,Huang, D.B.,Noro, B.,Thanos, D.,Ghosh, G. The kB DNA sequence from the HIV Long Terminal Repeat functions as an allosteric regulator of HIV transcription J.Biol.Chem., 277:24701-24708, 2002 Cited by PubMed: 11970949DOI: 10.1074/jbc.M200007200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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