PDB: 101 件ウェブページステータス検索Chemie searchBIRD

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7KW7	Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... 著者 Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. 登録日 2020-11-30 公開日 2021-12-08 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
7DHG	Crystal structure of SARS-CoV-2 Orf9b complex with human TOM70 分子名称: Mitochondrial import receptor subunit TOM70, ORF9b protein 著者 Gao, X, Zhu, K, Qin, B, Olieric, V, Wang, M, Cui, S. 登録日 2020-11-14 公開日 2021-05-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions. Nat Commun, 12, 2021
7KDT	Human Tom70 in complex with SARS CoV2 Orf9b 分子名称: Mitochondrial import receptor subunit TOM70, ORF9b protein 著者 QCRG Structural Biology Consortium 登録日 2020-10-09 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science, 370, 2020
7AIE	Crystal structure of a truncated form of the KLC1-TPR domain ([A1-B5] fragment) - Monoclinic crystal form 分子名称: Kinesin light chain 1, MAGNESIUM ION 著者 Menetrey, J, Llinas, P. 登録日 2020-09-27 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.287 Å) 主引用文献 Structural investigations of the dynamics of the TPR domain of kinesin light chain To Be Published
7AI4	Crystal structure of the KLC1-TPR domain truncated from its nonTPR region ([A1-B6]-Delta-nonTPR fragment) 分子名称: Isoform C of Kinesin light chain 1,Isoform C of Kinesin light chain 1 著者 Menetrey, J, Llinas, P. 登録日 2020-09-26 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.795 Å) 主引用文献 Structural investigations of the dynamics of the TPR domain of kinesin light chain To Be Published
6ZBK	Crystal structure of the human complex between RPAP3 and TRBP 分子名称: RISC-loading complex subunit TARBP2, RNA polymerase II-associated protein 3 著者 Charron, C, Abel, Y, Charpentier, B, Rederstorff, M. 登録日 2020-06-08 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity. Nucleic Acids Res., 50, 2022
6TNT	SUMOylated apoAPC/C with repositioned APC2 WHB domain 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Barford, D, Yatskevich, S. 登録日 2019-12-10 公開日 2021-01-13 最終更新日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation. Cell Rep, 34, 2021
6TM5	Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Alfieri, C, Barford, D. 登録日 2019-12-03 公開日 2020-02-19 最終更新日 2020-06-17 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase. Embo Rep., 21, 2020
6TLJ	Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Alfieri, C, Barford, D. 登録日 2019-12-02 公開日 2020-02-19 最終更新日 2020-06-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase. Embo Rep., 21, 2020
6Q6G	Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D1 box class 分子名称: Anaphase-promoting complex subunit 1,Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Zhang, S, Barford, D. 登録日 2018-12-11 公開日 2019-09-11 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nat Commun, 10, 2019
6Q6H	Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D2 box class 分子名称: Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 13, ... 著者 Zhang, S, Barford, D. 登録日 2018-12-11 公開日 2019-09-11 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nat Commun, 10, 2019
6I57	NMR structure of the third TPR domain of the human SPAG1 protein 分子名称: Sperm-associated antigen 1 著者 Chagot, M.E, Quinternet, M. 登録日 2018-11-13 公開日 2019-06-05 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Binding properties of the quaternary assembly protein SPAG1. Biochem.J., 476, 2019
6HFT	Hsp90 co-chaperone Cns1 from Saccharomyces cerevisiae (delta69) 分子名称: Hsp70/Hsp90 co-chaperone CNS1, MAGNESIUM ION 著者 Huber, E.M, Groll, M. 登録日 2018-08-21 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2. Mol.Cell, 74, 2019
6FUZ	Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1 分子名称: GLYCEROL, Kinesin light chain 1,Kinesin light chain 1,C-Jun-amino-terminal kinase-interacting protein 1, nanobody 著者 Pernigo, S, Dodding, M.P, Steiner, R.A. 登録日 2018-02-28 公開日 2018-05-02 最終更新日 2019-09-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors. Elife, 7, 2018
6FV0	Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of torsinA 分子名称: DI(HYDROXYETHYL)ETHER, Kinesin light chain 1,Torsin-1A, nanobody 著者 Pernigo, S, Dodding, M.P, Steiner, R.A. 登録日 2018-02-28 公開日 2018-03-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors. Elife, 7, 2018
6FO1	Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. 分子名称: ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ... 著者 Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O. 登録日 2018-02-05 公開日 2018-04-04 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nat Commun, 9, 2018
6FD7	NMR structure of the first TPR domain of the human RPAP3 protein 分子名称: RNA polymerase II-associated protein 3 著者 Quinternet, M, Chagot, M.E, Manival, X. 登録日 2017-12-22 公開日 2018-08-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. Structure, 26, 2018
6EOU	O-GlcNAc transferase TPR domain with the intellectual disability associated mutation L254F 分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 著者 Gundogdu, M, van Aalten, D.M.F. 登録日 2017-10-10 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix. Cell Chem Biol, 25, 2018
6EJN	The KLC2 TPR domain bound to the JIP3 leucine zipper domain 分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Kinesin light chain 2 著者 Cockburn, J, Hesketh, S.J, Way, M. 登録日 2017-09-22 公開日 2018-09-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3. Structure, 26, 2018
5OMP	Human FKBP5 protein 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, SULFATE ION 著者 Kumar, R, Moche, M, Winblad, B, Pavlov, P. 登録日 2017-08-01 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51. Sci Rep, 7, 2017
5OJ8	Crystal structure of the KLC1-TPR domain ([A1-B5] fragment) 分子名称: Kinesin light chain 1, PHOSPHATE ION 著者 Nguyen, T.Q, Chenon, M, Vilela, F, Velours, C, Fernandez-Varela, P, Llinas, P, Menetrey, J. 登録日 2017-07-20 公開日 2017-10-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.247 Å) 主引用文献 Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain. PLoS ONE, 12, 2017
5NJX	Human FKBP51 protein in complex with C-terminal peptide of Human HSP 90-alpha 分子名称: HSP90AA1 protein, Peptidyl-prolyl cis-trans isomerase FKBP5, SULFATE ION 著者 Kumar, R, Moche, M, Winblad, B, Pavlov, P. 登録日 2017-03-30 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51. Sci Rep, 7, 2017
5LYP	Crystal structure of the Tpr Domain of Sgt2. 分子名称: BORATE ION, Small glutamine-rich tetratricopeptide repeat-containing protein 2 著者 Krysztofinska, E.M, Morgan, R.M.L, Thapaliya, A, Evans, N.J, Murray, J.W, Martinez-Lumbreras, S, Isaacson, R.L. 登録日 2016-09-28 公開日 2017-10-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp. Front Mol Biosci, 4, 2017
5LYN	Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment 分子名称: PRO-THR-VAL-GLU-GLU-VAL-ASP, Small glutamine-rich tetratricopeptide repeat-containing protein 2, ZINC ION 著者 Krysztofinska, E.M, Evans, N.J, Thapaliya, A, Murray, J.W, Morgan, R.M.L, Martinez-Lumbreras, S, Isaacson, R.L. 登録日 2016-09-28 公開日 2017-10-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp. Front Mol Biosci, 4, 2017
5LCW	Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. 登録日 2016-06-22 公開日 2016-08-10 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Molecular basis of APC/C regulation by the spindle assembly checkpoint. Nature, 536, 2016

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