6Q6G
Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D1 box class
Summary for 6Q6G
Entry DOI | 10.2210/pdb6q6g/pdb |
EMDB information | 4463 4464 4465 4466 4467 |
Descriptor | Cell division cycle protein 20 homolog, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit CDC26, ... (16 entities in total) |
Functional Keywords | spindle assembly checkpoint, anaphase-promoting complex, cyclin, ubiquitination, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 21 |
Total formula weight | 1262721.05 |
Authors | Zhang, S.,Barford, D. (deposition date: 2018-12-11, release date: 2019-09-11, Last modification date: 2024-05-15) |
Primary citation | Zhang, S.,Tischer, T.,Barford, D. Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nat Commun, 10:3863-3863, 2019 Cited by PubMed: 31455778DOI: 10.1038/s41467-019-11833-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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