PDB: 287 resultsInfo pagesStatus searchChemie searchBIRD

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5W4E	Importin binding to Tdt NLS peptide Descriptor: GLYCEROL, Importin subunit alpha-1,Importin subunit alpha-1, human DNA repair polymerase Tdt Authors: Pedersen, L.C, London, R. Deposit date: 2017-06-10 Release date: 2018-06-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
5WUM	Crystal structure of mouse importin-alpha1 bound to S385-phosphorylated NLS of EBNA1 Descriptor: Epstein-Barr nuclear antigen 1, Importin subunit alpha-1 Authors: Nakada, R, Hirano, H, Matsuura, Y. Deposit date: 2016-12-19 Release date: 2017-01-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for the regulation of nuclear import of Epstein-Barr virus nuclear antigen 1 (EBNA1) by phosphorylation of the nuclear localization signal. Biochem. Biophys. Res. Commun., 484, 2017
5WUN	Crystal structure of mouse importin-alpha1 bound to non-phosphorylated NLS of EBNA1 Descriptor: Epstein-Barr nuclear antigen 1, Importin subunit alpha-1 Authors: Nakada, R, Hirano, H, Matsuura, Y. Deposit date: 2016-12-19 Release date: 2017-01-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for the regulation of nuclear import of Epstein-Barr virus nuclear antigen 1 (EBNA1) by phosphorylation of the nuclear localization signal. Biochem. Biophys. Res. Commun., 484, 2017
3ZIN	Gu_alpha_helicase Descriptor: IMPORTIN SUBUNIT ALPHA-2, NUCLEOLAR RNA HELICASE 2 Authors: Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. Deposit date: 2013-01-10 Release date: 2013-08-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
3ZIR	minor-site specific NLS (B141) Descriptor: B141NLS, IMPORTIN SUBUNIT ALPHA-2 Authors: Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. Deposit date: 2013-01-10 Release date: 2013-08-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
3ZIQ	minor-site specific NLS (B6) Descriptor: B6NLS, IMPORTIN SUBUNIT ALPHA-2 Authors: Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. Deposit date: 2013-01-10 Release date: 2013-08-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
3ZIP	minor-site specific NLS (A58) Descriptor: A58NLS, IMPORTIN SUBUNIT ALPHA-2 Authors: Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. Deposit date: 2013-01-10 Release date: 2013-08-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
3ZIO	minor-site specific NLS (A28) Descriptor: A28NLS, IMPORTIN SUBUNIT ALPHA-2 Authors: Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. Deposit date: 2013-01-10 Release date: 2013-08-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
4B18	The crystal structure of human Importin alpha 5 with TERT NLS peptide Descriptor: IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE Authors: Kim, K.L, Yoo, J.H, Cho, H.S. Deposit date: 2012-07-08 Release date: 2013-09-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation. J.Cell.Sci., 128, 2015
4B8O	rImp_alpha_SV40TAgNLS Descriptor: IMPORTIN SUBUNIT ALPHA-1A, SV40TAGNLS Authors: Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. Deposit date: 2012-08-28 Release date: 2013-01-09 Last modified: 2013-02-20 Method: X-RAY DIFFRACTION (2.084 Å) Cite: Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
4B8P	rImp_alpha_A89NLS Descriptor: A89NLS, IMPORTIN SUBUNIT ALPHA-1A Authors: Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. Deposit date: 2012-08-29 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
4BA3	mImp_alphadIBB_A89NLS Descriptor: A89NLS, IMPORTIN SUBUNIT ALPHA-2 Authors: Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. Deposit date: 2012-09-11 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
4B8J	rImp_alpha1a Descriptor: IMPORTIN SUBUNIT ALPHA-1A Authors: Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. Deposit date: 2012-08-28 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
4BPL	rice importin_alpha in complex with nucleoplasmin NLS Descriptor: IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS Authors: Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. Deposit date: 2013-05-27 Release date: 2014-02-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha Mol.Plant, 7, 2014
4BQK	rice importin_alpha : VirD2NLS complex Descriptor: DI(HYDROXYETHYL)ETHER, IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER ENDONUCLEASE VIRD2 Authors: Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. Deposit date: 2013-05-31 Release date: 2014-02-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.997 Å) Cite: Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha Mol.Plant, 7, 2014
4E4V	The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-2 Authors: Hang, P.C, Miknis, Z.M, Franke, W.A, Umland, T.C, Schultz, L.W. Deposit date: 2012-03-13 Release date: 2013-05-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5283 Å) Cite: The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. To be Published
4PVZ	Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 Descriptor: Importin subunit alpha, Inner nuclear membrane protein HEH2 Authors: Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C. Deposit date: 2014-03-18 Release date: 2015-08-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23, 2015
4RXH	Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS Descriptor: Importin subunit alpha, Large T antigen Authors: Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2014-12-11 Release date: 2015-07-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7553 Å) Cite: Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal. Plos One, 10, 2015
4TNM	Crystal structure of Arabidopsis importin-alpha3 armadillo repeat domain Descriptor: Importin subunit alpha Authors: Wirthmueller, L, Banfield, M. Deposit date: 2014-06-04 Release date: 2014-10-08 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Probing formation of cargo/importin-alpha transport complexes in plant cells using a pathogen effector. Plant J., 81, 2015
4UAF	Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain Descriptor: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2 Authors: Pumroy, R.A, Cingolani, G. Deposit date: 2014-08-08 Release date: 2015-02-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
4U2X	Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus Descriptor: CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24 Authors: Xu, W, Leung, D, Borek, D, Amarasinghe, G. Deposit date: 2014-07-18 Release date: 2014-08-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.153 Å) Cite: Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host Microbe, 16, 2014
4U5L	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2015-07-08 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5V	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2015-07-08 Method: X-RAY DIFFRACTION (1.968 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5N	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2015-07-08 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5S	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR Descriptor: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide Authors: Stewart, M, Valkov, E, Holvey, R.S. Deposit date: 2014-07-25 Release date: 2015-05-13 Last modified: 2017-06-21 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015

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